Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

2000 candidates match the current filter; 10 are shown per page (page 170 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
TkA07G359520
TK1151: TkA07G359520
OH-1004: LXL04_018704
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-Prot CM104802.1:17162251-17165589
-
go:0010078 maintenance of root meristem identity biological_process
TkA08G081190
TK1151: TkA08G081190
OH-1004: LXL04_018755
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104802.1:17661495-17665346
+
go:0010078 maintenance of root meristem identity biological_process
TkA08G082490
TK1151: TkA08G082490
OH-1004: LXL04_018774
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104802.1:18005839-18016286
+
go:0006970 response to osmotic stress biological_process
TkA08G082650
TK1151: TkA08G082650
OH-1004: LXL04_018776
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104802.1:18112146-18116452
+
go:0006970 response to osmotic stress biological_process
TkA08G083330
TK1151: TkA08G083330
OH-1004: LXL04_018792
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104802.1:18314118-18314972
-
go:0009611 response to wounding biological_process
TkA05G002630
TK1151: TkA05G002630;TkA08G087740
OH-1004: LXL04_018881
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104802.1:19577076-19577814
+
go:0009611 response to wounding biological_process
TkA05G004070
TK1151: TkA05G004070
OH-1004: LXL04_018917
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-Prot CM104802.1:20011726-20013325
+
go:0010082 regulation of root meristem growth biological_process
TkA05G004450
TK1151: TkA05G004450
OH-1004: LXL04_018924
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104802.1:20090722-20092512
+
go:0006970 response to osmotic stress biological_process
TkA05G005240
TK1151: TkA05G005240
OH-1004: LXL04_018952
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104802.1:20348841-20350378
+
go:0006970 response to osmotic stress biological_process
TkA02G373230
TK1151: TkA02G373230;TkA05G007160;TkA05G007170
OH-1004: LXL04_018981
Latex/root related candidates
Latex/root associated candidates
Medium
score 4
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104802.1:20901154-20903151
+
go:0048364 root development biological_process

TkA07G359520

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA07G359520
LocationCM104802.1:17162251-17165589 -
EvidenceGOExpressionLocalizationPfamSwiss-Prot
Key evidencego:0010078 maintenance of root meristem identity biological_process

TkA08G081190

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA08G081190
LocationCM104802.1:17661495-17665346 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010078 maintenance of root meristem identity biological_process

TkA08G082490

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA08G082490
LocationCM104802.1:18005839-18016286 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA08G082650

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA08G082650
LocationCM104802.1:18112146-18116452 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA08G083330

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA08G083330
LocationCM104802.1:18314118-18314972 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0009611 response to wounding biological_process

TkA05G002630

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA05G002630;TkA08G087740
LocationCM104802.1:19577076-19577814 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0009611 response to wounding biological_process

TkA05G004070

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA05G004070
LocationCM104802.1:20011726-20013325 +
EvidenceGOExpressionLocalizationPfamSwiss-Prot
Key evidencego:0010082 regulation of root meristem growth biological_process

TkA05G004450

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA05G004450
LocationCM104802.1:20090722-20092512 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA05G005240

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA05G005240
LocationCM104802.1:20348841-20350378 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA02G373230

Latex/root related candidatesLatex/root associated candidatesMedium · score 4
Source IDTkA02G373230;TkA05G007160;TkA05G007170
LocationCM104802.1:20901154-20903151 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0048364 root development biological_process

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.