Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

8 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisopreneRNAi laticifers with polymer and particle assaysTbCPT1JQ991925.1CPTCPT/CPTL branchLaticifer-specific cis-prenyltransferaseA_direct_experiment
TbCPT1 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion.
External evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz.
10.1104/pp.111.187880Laticifer-specific cis-prenyltransferase silencing affects natural rubber biosynthesis in Taraxacum brevicorniculatum
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisopreneRNAi laticifers with polymer and particle assaysTbCPT2JQ991926.1CPTCPT/CPTL branchLaticifer-specific cis-prenyltransferaseA_direct_experiment
TbCPT2 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion.
External evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz.
10.1104/pp.111.187880Laticifer-specific cis-prenyltransferase silencing affects natural rubber biosynthesis in Taraxacum brevicorniculatum
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisopreneRNAi laticifers with polymer and particle assaysTbCPT3JQ991927.1CPTCPT/CPTL branchLaticifer-specific cis-prenyltransferaseA_direct_experiment
TbCPT3 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion.
External evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz.
10.1104/pp.111.187880Laticifer-specific cis-prenyltransferase silencing affects natural rubber biosynthesis in Taraxacum brevicorniculatum
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisopreneRubber-particle extraction and heterologous assaysTbSRPP1JQ991928.1SRPPREF/SRPP rubber-particle proteinsSmall rubber-particle proteinA_direct_experiment
TbSRPP1 is a direct experimental reference associated with rubber-particle formation.
External particle-protein evidence, not direct validation in T. kok-saghyz.
10.1111/tpj.13829Small rubber particle proteins from Taraxacum brevicorniculatum are associated with rubber particle formation
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisoprenePublic cDNA recordsTbRTAKP763637.1RTALatex/root associatedRubber transferase activator referenceB_sequence_resource
Sequence records support exact ID lookup and future homology mapping but do not independently establish function.
Sequence record alone is not functional proof.
KP763637.1;MF471639.1;KJ911908.1;KJ911910.1Taraxacum brevicorniculatum rubber pathway sequence records
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisoprenePublic cDNA recordsTbFDPS1KJ911908.1FDPSPrenyl-donor metabolismPrenyl-donor synthesis referenceB_sequence_resource
Sequence records support exact ID lookup and future homology mapping but do not independently establish function.
Sequence record alone is not functional proof.
KP763637.1;MF471639.1;KJ911908.1;KJ911910.1Taraxacum brevicorniculatum rubber pathway sequence records
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisoprenePublic cDNA recordsTbFDPS2KJ911910.1FDPSPrenyl-donor metabolismPrenyl-donor synthesis referenceB_sequence_resource
Sequence records support exact ID lookup and future homology mapping but do not independently establish function.
Sequence record alone is not functional proof.
KP763637.1;MF471639.1;KJ911908.1;KJ911910.1Taraxacum brevicorniculatum rubber pathway sequence records
Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisoprenePublic cDNA recordsTbREFMF471639.1REFREF/SRPP rubber-particle proteinsRubber-particle protein referenceB_sequence_resource
Sequence records support exact ID lookup and future homology mapping but do not independently establish function.
Sequence record alone is not functional proof.
KP763637.1;MF471639.1;KJ911908.1;KJ911910.1Taraxacum brevicorniculatum rubber pathway sequence records

Laticiferous dandelion · TbCPT1

Sequence IDJQ991925.1
StepCPT/CPTL branch · CPT
EvidenceTbCPT1 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion.
BoundaryExternal evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz.

Laticiferous dandelion · TbCPT2

Sequence IDJQ991926.1
StepCPT/CPTL branch · CPT
EvidenceTbCPT2 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion.
BoundaryExternal evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz.

Laticiferous dandelion · TbCPT3

Sequence IDJQ991927.1
StepCPT/CPTL branch · CPT
EvidenceTbCPT3 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion.
BoundaryExternal evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz.

Laticiferous dandelion · TbSRPP1

Sequence IDJQ991928.1
StepREF/SRPP rubber-particle proteins · SRPP
EvidenceTbSRPP1 is a direct experimental reference associated with rubber-particle formation.
BoundaryExternal particle-protein evidence, not direct validation in T. kok-saghyz.

Laticiferous dandelion · TbRTA

Sequence IDKP763637.1
StepLatex/root associated · RTA
EvidenceSequence records support exact ID lookup and future homology mapping but do not independently establish function.
BoundarySequence record alone is not functional proof.

Laticiferous dandelion · TbFDPS1

Sequence IDKJ911908.1
StepPrenyl-donor metabolism · FDPS
EvidenceSequence records support exact ID lookup and future homology mapping but do not independently establish function.
BoundarySequence record alone is not functional proof.

Laticiferous dandelion · TbFDPS2

Sequence IDKJ911910.1
StepPrenyl-donor metabolism · FDPS
EvidenceSequence records support exact ID lookup and future homology mapping but do not independently establish function.
BoundarySequence record alone is not functional proof.

Laticiferous dandelion · TbREF

Sequence IDMF471639.1
StepREF/SRPP rubber-particle proteins · REF
EvidenceSequence records support exact ID lookup and future homology mapping but do not independently establish function.
BoundarySequence record alone is not functional proof.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

2000 candidates match the current filter; 10 are shown per page (page 11 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
TkA01G561850
TK1151: TkA01G561850
OH-1004: LXL04_001090
MVA/MEP and isoprenoid
Prenyl-donor metabolism
High
score 10
FunctionGOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:19989751-19992525
-
go:0009824 amp dimethylallyltransferase activity molecular_function
TkA01G526400
TK1151: TkA01G526400
OH-1004: LXL04_001550
MVA/MEP and isoprenoid
Prenyl-donor metabolism
High
score 10
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104799.1:28958260-28959614
+
GO:0006720
TkA01G522970
TK1151: TkA01G522970
OH-1004: LXL04_001598
MVA/MEP and isoprenoid
Mevalonate pathway
High
score 10
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:29822753-29827340
-
GO:0008299
TkA01G492590
TK1151: TkA01G492590
OH-1004: LXL04_002002
Latex/root related candidates
Latex/root associated candidates
High
score 10
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:38809573-38810232
-
go:0006970 response to osmotic stress biological_process
TkA01G475480
TK1151: TkA01G475480;TkA07G186220;TkA07G186860
OH-1004: LXL04_002187
Terpenoid metabolism
Terpenoid metabolism
High
score 10
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:43509327-43511401
+
GO:0010333
TkA01G402800
TK1151: TkA01G402800
OH-1004: LXL04_003034
Terpenoid metabolism
Terpenoid metabolism
High
score 10
FunctionGOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:65386113-65404532
-
go:0010686 tetracyclic triterpenoid biosynthetic process biological_process
LXL04_003040
TK1151: -
OH-1004: LXL04_003040
MVA/MEP and isoprenoid
Prenyl-donor metabolism
High
score 10
GOExpressionLocalizationSwiss-Prot CM104799.1:65621689-65621968
-
GO:0016114
TkA01G387270
TK1151: TkA01G387270;TkA01G556620;TkA08G142540
OH-1004: LXL04_003181
MVA/MEP and isoprenoid
Prenyl-donor metabolism
High
score 10
FunctionGOExpressionLocalizationPfamSwiss-ProtCoexpression CM104799.1:70368002-70371154
-
go:0004311 geranylgeranyl diphosphate synthase activity molecular_function
TkA01G105050
TK1151: TkA01G105050
OH-1004: LXL04_004824
Latex/root related candidates
Latex/root associated candidates
High
score 10
GOExpressionLocalizationPfamSwiss-ProtPPI CM104799.1:147918774-147922111
-
go:0010015 root morphogenesis biological_process
TkA01G095270
TK1151: TkA01G095270
OH-1004: LXL04_004939
MVA/MEP and isoprenoid
Prenyl-donor metabolism
High
score 10
FunctionGOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104799.1:150602539-150603477
+
go:0004663 rab geranylgeranyltransferase activity molecular_function

TkA01G561850

MVA/MEP and isoprenoidPrenyl-donor metabolismHigh · score 10
Source IDTkA01G561850
LocationCM104799.1:19989751-19992525 -
EvidenceFunctionGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0009824 amp dimethylallyltransferase activity molecular_function

TkA01G526400

MVA/MEP and isoprenoidPrenyl-donor metabolismHigh · score 10
Source IDTkA01G526400
LocationCM104799.1:28958260-28959614 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0006720

TkA01G522970

MVA/MEP and isoprenoidMevalonate pathwayHigh · score 10
Source IDTkA01G522970
LocationCM104799.1:29822753-29827340 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0008299

TkA01G492590

Latex/root related candidatesLatex/root associated candidatesHigh · score 10
Source IDTkA01G492590
LocationCM104799.1:38809573-38810232 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0006970 response to osmotic stress biological_process

TkA01G475480

Terpenoid metabolismTerpenoid metabolismHigh · score 10
Source IDTkA01G475480;TkA07G186220;TkA07G186860
LocationCM104799.1:43509327-43511401 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0010333

TkA01G402800

Terpenoid metabolismTerpenoid metabolismHigh · score 10
Source IDTkA01G402800
LocationCM104799.1:65386113-65404532 -
EvidenceFunctionGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010686 tetracyclic triterpenoid biosynthetic process biological_process

LXL04_003040

MVA/MEP and isoprenoidPrenyl-donor metabolismHigh · score 10
Source ID-
LocationCM104799.1:65621689-65621968 -
EvidenceGOExpressionLocalizationSwiss-Prot
Key evidenceGO:0016114

TkA01G387270

MVA/MEP and isoprenoidPrenyl-donor metabolismHigh · score 10
Source IDTkA01G387270;TkA01G556620;TkA08G142540
LocationCM104799.1:70368002-70371154 -
EvidenceFunctionGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidencego:0004311 geranylgeranyl diphosphate synthase activity molecular_function

TkA01G105050

Latex/root related candidatesLatex/root associated candidatesHigh · score 10
Source IDTkA01G105050
LocationCM104799.1:147918774-147922111 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPI
Key evidencego:0010015 root morphogenesis biological_process

TkA01G095270

MVA/MEP and isoprenoidPrenyl-donor metabolismHigh · score 10
Source IDTkA01G095270
LocationCM104799.1:150602539-150603477 +
EvidenceFunctionGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0004663 rab geranylgeranyltransferase activity molecular_function

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.