Para rubber tree · HRBP
Sequence IDLC057267
StepCPT/CPTL branch · CPTL
EvidenceHRBP was reported as a helper subunit in the HRT1 rubber-particle complex.
BoundaryComplex-support evidence, not a stand-alone catalytic claim.
Source10.7554/eLife.19022
A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.
The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.
22 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.
| Species and material | Reference gene / sequence ID | Pathway step | Evidence and boundary | Source |
|---|---|---|---|---|
| Para rubber treeHevea brasiliensiscis-1,4-polyisopreneRubber particles | HRBPLC057267CPTL | CPT/CPTL branchHRT1-complex helper subunit | A_direct_experiment HRBP was reported as a helper subunit in the HRT1 rubber-particle complex. Complex-support evidence, not a stand-alone catalytic claim. | 10.7554/eLife.19022Identification and reconstitution of the rubber biosynthetic machinery on rubber particles from Hevea brasiliensis |
| Para rubber treeHevea brasiliensiscis-1,4-polyisopreneRubber particles | HRT1BAB71776.2;AB061234.3CPT | CPT/CPTL branchRubber-particle cis-prenyltransferase | A_direct_experiment HRT1 showed in-vitro rubber-transferase activity on detergent-washed rubber particles, with higher activity for the HRT1-REF-HRBP complex. Direct evidence in Hevea rubber particles; not direct validation in rubber dandelion. | 10.7554/eLife.19022Identification and reconstitution of the rubber biosynthetic machinery on rubber particles from Hevea brasiliensis |
| GuayuleParthenium argentatumcis-1,4-polyisoprenePI478663 and heterologous systems | PaCBPMF688938;ATD87120CPTL | CPT/CPTL branchGuayule CPT-complex helper subunit | A_direct_experiment PaCPT/PaCBP complex evidence is displayed with its in-vitro and heterologous-system boundary. Helper-subunit evidence must retain the assay context. | 10.3389/fpls.2019.00165Characterization of cis-prenyltransferases and cis-prenyltransferase-like protein from guayule |
| GuayuleParthenium argentatumcis-1,4-polyisoprenePI478663 and heterologous systems | PaCPT1MF688933;ATD87115CPT | CPT/CPTL branchForms a cis-prenyltransferase complex with PaCBP | A_direct_experiment PaCPT1 and PaCBP formed an active cis-prenyltransferase complex in heterologous and in-vitro systems. Assay-dependent external evidence; not in-plant rubber-yield proof. | 10.3389/fpls.2019.00165Characterization of cis-prenyltransferases and cis-prenyltransferase-like protein from guayule |
| GuayuleParthenium argentatumcis-1,4-polyisoprenePI478663 and heterologous systems | PaCPT2MF688936;ATD87118CPT | CPT/CPTL branchForms a cis-prenyltransferase complex with PaCBP | A_direct_experiment PaCPT/PaCBP complex evidence is displayed with its in-vitro and heterologous-system boundary. Do not equate short-chain in-vitro activity with in-plant rubber yield. | 10.3389/fpls.2019.00165Characterization of cis-prenyltransferases and cis-prenyltransferase-like protein from guayule |
| GuayuleParthenium argentatumcis-1,4-polyisoprenePI478663 and heterologous systems | PaCPT3MF688934;ATD87116CPT | CPT/CPTL branchForms a cis-prenyltransferase complex with PaCBP | A_direct_experiment PaCPT/PaCBP complex evidence is displayed with its in-vitro and heterologous-system boundary. Do not equate short-chain in-vitro activity with in-plant rubber yield. | 10.3389/fpls.2019.00165Characterization of cis-prenyltransferases and cis-prenyltransferase-like protein from guayule |
| Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisopreneRNAi laticifers with polymer and particle assays | TbCPT1JQ991925.1CPT | CPT/CPTL branchLaticifer-specific cis-prenyltransferase | A_direct_experiment TbCPT1 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion. External evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz. | 10.1104/pp.111.187880Laticifer-specific cis-prenyltransferase silencing affects natural rubber biosynthesis in Taraxacum brevicorniculatum |
| Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisopreneRNAi laticifers with polymer and particle assays | TbCPT2JQ991926.1CPT | CPT/CPTL branchLaticifer-specific cis-prenyltransferase | A_direct_experiment TbCPT2 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion. External evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz. | 10.1104/pp.111.187880Laticifer-specific cis-prenyltransferase silencing affects natural rubber biosynthesis in Taraxacum brevicorniculatum |
| Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisopreneRNAi laticifers with polymer and particle assays | TbCPT3JQ991927.1CPT | CPT/CPTL branchLaticifer-specific cis-prenyltransferase | A_direct_experiment TbCPT3 is a direct laticifer-specific cis-rubber experimental reference in a related dandelion. External evidence in T. brevicorniculatum, not direct validation in T. kok-saghyz. | 10.1104/pp.111.187880Laticifer-specific cis-prenyltransferase silencing affects natural rubber biosynthesis in Taraxacum brevicorniculatum |
| Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisopreneRubber-particle extraction and heterologous assays | TbSRPP1JQ991928.1SRPP | REF/SRPP rubber-particle proteinsSmall rubber-particle protein | A_direct_experiment TbSRPP1 is a direct experimental reference associated with rubber-particle formation. External particle-protein evidence, not direct validation in T. kok-saghyz. | 10.1111/tpj.13829Small rubber particle proteins from Taraxacum brevicorniculatum are associated with rubber particle formation |
| Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic roots | EuIPIAB041629.2IDI | Prenyl-donor metabolismTrans-polyisoprene precursor-supply reference | A_direct_genetic_experiment EuIPI overexpression was associated with higher trans-polyisoprene accumulation. Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions. | 10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation |
| GuayuleParthenium argentatumcis-1,4-polyisopreneAOS RNAi and overexpression plants | AOS1X78166.2CYP74 | Latex/root associatedRegulatory candidate associated with rubber content and transferase activity | A_direct_genetic_experiment AOS down-regulation was associated with higher rubber content and rubber-transferase activity. RNAi specificity limitation remains; do not infer a single-gene universal mechanism. | 10.3389/fpls.2019.00760Silencing of allene oxide synthase in guayule increases rubber content and rubber transferase activity |
| Para rubber treeHevea brasiliensiscis-1,4-polyisopreneLatex and recombinant enzyme | HRT2Q8W3U4;AB064661.2CPT | CPT/CPTL branchLatex-expressed cis-prenyltransferase reference | A_enzyme_experiment HRT2 is retained as a cis-prenyltransferase and latex-expression reference. Do not claim direct reconstitution of high-molecular-weight natural rubber by HRT2 alone. | 10.1046/j.1432-1033.2003.03863.xMolecular cloning expression and characterization of cDNA encoding cis-prenyltransferases from Hevea brasiliensis |
| Para rubber treeHevea brasiliensiscis-1,4-polyisopreneRubber particles | REFREF complex memberREF | REF/SRPP rubber-particle proteinsRubber-particle complex member | A_complex_evidence HRT1 and HRBP/REF particle-complex evidence; REF is not displayed as a stand-alone catalytic proof. Not a stand-alone catalytic proof. | 10.7554/eLife.19022Identification and reconstitution of the rubber biosynthetic machinery on rubber particles from Hevea brasiliensis |
| GuayuleParthenium argentatumcis-1,4-polyisopreneAZ-3 field bark under well-watered and drought conditions | PaCBPPaTc_149493CPTL | CPT/CPTL branchCBP transcript reference in drought transcriptomics | B_omics_association PaCBP was reported in field bark transcriptomics under contrasting irrigation. Association only; transcript abundance is not direct proof of rubber yield. | 10.1038/s41598-021-01026-7Transcriptomic analysis of guayule bark under contrasting irrigation conditions |
| GuayuleParthenium argentatumcis-1,4-polyisopreneAZ-3 field bark under well-watered and drought conditions | PaCPT1PaTc_044561CPT | CPT/CPTL branchCPT1 transcript reference in drought transcriptomics | B_omics_association PaCPT1 was reported in field bark transcriptomics under contrasting irrigation. Association only; transcript abundance is not direct proof of rubber yield. | 10.1038/s41598-021-01026-7Transcriptomic analysis of guayule bark under contrasting irrigation conditions |
| GuayuleParthenium argentatumcis-1,4-polyisopreneAZ-3 field bark under well-watered and drought conditions | PaSRPP1PaTc_109994SRPP | REF/SRPP rubber-particle proteinsSRPP1 transcript reference in drought transcriptomics | B_omics_association Expression association is not converted into causal rubber-yield evidence. Transcript abundance is not direct proof of rubber yield. | 10.1038/s41598-021-01026-7Transcriptomic analysis of guayule bark under contrasting irrigation conditions |
| GuayuleParthenium argentatumcis-1,4-polyisopreneSRPP1 promoter reporter assay | PaSRPP1 promoterPV754023.1SRPP | REF/SRPP rubber-particle proteinsSRPP1 promoter regulatory reference | A_promoter_experiment Promoter sequence is regulatory reference evidence, not a complete gene-model crosswalk. Promoter record is not a complete SRPP1 gene model. | 10.1186/s13104-025-07448-0Functional characterization of the guayule SRPP1 promoter |
| Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisoprenePublic cDNA records | TbRTAKP763637.1RTA | Latex/root associatedRubber transferase activator reference | B_sequence_resource Sequence records support exact ID lookup and future homology mapping but do not independently establish function. Sequence record alone is not functional proof. | KP763637.1;MF471639.1;KJ911908.1;KJ911910.1Taraxacum brevicorniculatum rubber pathway sequence records |
| Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisoprenePublic cDNA records | TbFDPS1KJ911908.1FDPS | Prenyl-donor metabolismPrenyl-donor synthesis reference | B_sequence_resource Sequence records support exact ID lookup and future homology mapping but do not independently establish function. Sequence record alone is not functional proof. | KP763637.1;MF471639.1;KJ911908.1;KJ911910.1Taraxacum brevicorniculatum rubber pathway sequence records |
| Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisoprenePublic cDNA records | TbFDPS2KJ911910.1FDPS | Prenyl-donor metabolismPrenyl-donor synthesis reference | B_sequence_resource Sequence records support exact ID lookup and future homology mapping but do not independently establish function. Sequence record alone is not functional proof. | KP763637.1;MF471639.1;KJ911908.1;KJ911910.1Taraxacum brevicorniculatum rubber pathway sequence records |
| Laticiferous dandelionTaraxacum brevicorniculatumcis-1,4-polyisoprenePublic cDNA records | TbREFMF471639.1REF | REF/SRPP rubber-particle proteinsRubber-particle protein reference | B_sequence_resource Sequence records support exact ID lookup and future homology mapping but do not independently establish function. Sequence record alone is not functional proof. | KP763637.1;MF471639.1;KJ911908.1;KJ911910.1Taraxacum brevicorniculatum rubber pathway sequence records |
2000 candidates match the current filter; 10 are shown per page (page 11 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.
| Gene ID | Pathway/step | Confidence | Evidence layers | Location | Key evidence | Actions |
|---|---|---|---|---|---|---|
TkA01G561850TK1151: TkA01G561850 OH-1004: LXL04_001090 |
MVA/MEP and isoprenoid Prenyl-donor metabolism |
High score 10 |
FunctionGOExpressionLocalizationPfamSwiss-ProtPPICoexpression | CM104799.1:19989751-19992525 - |
go:0009824 amp dimethylallyltransferase activity molecular_function | |
TkA01G526400TK1151: TkA01G526400 OH-1004: LXL04_001550 |
MVA/MEP and isoprenoid Prenyl-donor metabolism |
High score 10 |
GOExpressionLocalizationPfamSwiss-ProtCoexpression | CM104799.1:28958260-28959614 + |
GO:0006720 | |
TkA01G522970TK1151: TkA01G522970 OH-1004: LXL04_001598 |
MVA/MEP and isoprenoid Mevalonate pathway |
High score 10 |
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression | CM104799.1:29822753-29827340 - |
GO:0008299 | |
TkA01G492590TK1151: TkA01G492590 OH-1004: LXL04_002002 |
Latex/root related candidates Latex/root associated candidates |
High score 10 |
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression | CM104799.1:38809573-38810232 - |
go:0006970 response to osmotic stress biological_process | |
TkA01G475480TK1151: TkA01G475480;TkA07G186220;TkA07G186860 OH-1004: LXL04_002187 |
Terpenoid metabolism Terpenoid metabolism |
High score 10 |
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression | CM104799.1:43509327-43511401 + |
GO:0010333 | |
TkA01G402800TK1151: TkA01G402800 OH-1004: LXL04_003034 |
Terpenoid metabolism Terpenoid metabolism |
High score 10 |
FunctionGOExpressionLocalizationPfamSwiss-ProtPPICoexpression | CM104799.1:65386113-65404532 - |
go:0010686 tetracyclic triterpenoid biosynthetic process biological_process | |
LXL04_003040TK1151: - OH-1004: LXL04_003040 |
MVA/MEP and isoprenoid Prenyl-donor metabolism |
High score 10 |
GOExpressionLocalizationSwiss-Prot | CM104799.1:65621689-65621968 - |
GO:0016114 | |
TkA01G387270TK1151: TkA01G387270;TkA01G556620;TkA08G142540 OH-1004: LXL04_003181 |
MVA/MEP and isoprenoid Prenyl-donor metabolism |
High score 10 |
FunctionGOExpressionLocalizationPfamSwiss-ProtCoexpression | CM104799.1:70368002-70371154 - |
go:0004311 geranylgeranyl diphosphate synthase activity molecular_function | |
TkA01G105050TK1151: TkA01G105050 OH-1004: LXL04_004824 |
Latex/root related candidates Latex/root associated candidates |
High score 10 |
GOExpressionLocalizationPfamSwiss-ProtPPI | CM104799.1:147918774-147922111 - |
go:0010015 root morphogenesis biological_process | |
TkA01G095270TK1151: TkA01G095270 OH-1004: LXL04_004939 |
MVA/MEP and isoprenoid Prenyl-donor metabolism |
High score 10 |
FunctionGOExpressionLocalizationPfamSwiss-ProtPPICoexpression | CM104799.1:150602539-150603477 + |
go:0004663 rab geranylgeranyltransferase activity molecular_function |
TkA01G561850TkA01G526400TkA01G522970TkA01G492590TkA01G475480TkA01G402800LXL04_003040TkA01G387270TkA01G105050TkA01G095270Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.