Rubber Biosynthesis Focus

A pathway-centered entry for MVA/MEP, IPP/DMAPP, prenyl donors, CPT/CPTL, REF/SRPP, latex/root-associated and terpenoid candidate genes.

This topic is built from precomputed GFF/GO/KEGG/homology candidate sets and linked evidence from expression, proteome, localization, Pfam, Swiss-Prot, PPI, coexpression and TFBS modules. Results are candidate evidence, not experimental validation.

The current database contains 5523 candidate records, 4979 candidate genes, and 8 pathway steps; the main display is centered on the TK1151 reference while OH-1004/LXL04 remains queryable and linked.

Cross-species Research Reference

1 reference genes are counted separately from rubber-dandelion candidates. They are literature, omics, or sequence resources from Para rubber tree, guayule, a related dandelion, and Eucommia; external function or homology is not direct validation in rubber dandelion.

1. Choose a speciesClick a species card or use the filter to focus on one reference species and material context.
2. Read the evidence typeRead the evidence and boundary column: direct experiments, omics associations, and sequence resources have different interpretation ranges.
3. Verify the sourceEach DOI, article, or public database entry is clickable; download the current filter for further comparison.
Eucommia records are a trans-polyisoprene comparator only and are excluded from natural cis-rubber candidate and pathway-card counts.
Species and materialReference gene / sequence IDPathway stepEvidence and boundarySource
Hardy rubber treeEucommia ulmoidestrans-1,4-polyisopreneTransgenic rootsEuIPIAB041629.2IDIPrenyl-donor metabolismTrans-polyisoprene precursor-supply referenceA_direct_genetic_experiment
EuIPI overexpression was associated with higher trans-polyisoprene accumulation.
Trans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.
10.1186/1472-6750-12-78Overexpression of EuIPI increases trans-polyisoprene accumulation

Hardy rubber tree · EuIPI

Sequence IDAB041629.2
StepPrenyl-donor metabolism · IDI
EvidenceEuIPI overexpression was associated with higher trans-polyisoprene accumulation.
BoundaryTrans-polyisoprene comparator only; excluded from natural cis-rubber candidate conclusions.

Pathway Navigation And Candidate Distribution

377 MVA/MEP and isoprenoid
Click to filter · High 204 · Medium 86 · Low 87
4466 Latex/root related candidates
Click to filter · High 231 · Medium 1284 · Low 2951
300 Rubber biosynthesis
Click to filter · High 1 · Medium 287 · Low 12
380 Terpenoid metabolism
Click to filter · High 72 · Medium 107 · Low 201

Candidate Genes

2000 candidates match the current filter; 10 are shown per page (page 103 of 200). TSV exports up to 2000 rows under the current filters. Use pathway nodes or summary cards to filter, then inspect Gene Card and linked modules for evidence details.

Gene IDPathway/stepConfidenceEvidence layersLocationKey evidenceActions
TkA08G164190
TK1151: TkA08G164190
OH-1004: LXL04_032305
MVA/MEP and isoprenoid
Prenyl-donor metabolism
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104805.1:20122314-20123924
+
GO:0016114
TkA08G164190
TK1151: TkA08G164190
OH-1004: LXL04_032305
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104805.1:20122314-20123924
+
GO:0016114
LXL04_032307
TK1151: -
OH-1004: LXL04_032307
MVA/MEP and isoprenoid
Prenyl-donor metabolism
Medium
score 6
GOExpressionLocalizationPfamSwiss-Prot CM104805.1:20171877-20173499
+
GO:0016114
LXL04_032307
TK1151: -
OH-1004: LXL04_032307
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-Prot CM104805.1:20171877-20173499
+
GO:0016114
TkA08G170700
TK1151: TkA08G170700
OH-1004: LXL04_032384
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtCoexpression CM104805.1:21614998-21617777
-
GO:0016740
LXL04_032401
TK1151: -
OH-1004: LXL04_032401
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationSwiss-ProtCoexpression CM104805.1:21793061-21796603
-
GO:0008299
TkA08G173390
TK1151: TkA08G173390
OH-1004: LXL04_032417
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104805.1:22434147-22437118
+
go:0010082 regulation of root meristem growth biological_process
TkA08G173400
TK1151: TkA08G173400
OH-1004: LXL04_032418
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104805.1:22440538-22443336
-
go:0010053 root epidermal cell differentiation biological_process
LXL04_032501
TK1151: -
OH-1004: LXL04_032501
Latex/root related candidates
Latex/root associated candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104805.1:24117074-24120869
-
go:0010078 maintenance of root meristem identity biological_process
TkAUNG016680
TK1151: TkAUNG016680;TkA08G189430
OH-1004: LXL04_032581
Rubber biosynthesis
Rubber biosynthesis candidates
Medium
score 6
GOExpressionLocalizationPfamSwiss-ProtPPICoexpression CM104805.1:25800364-25802598
+
GO:0016740

TkA08G164190

MVA/MEP and isoprenoidPrenyl-donor metabolismMedium · score 6
Source IDTkA08G164190
LocationCM104805.1:20122314-20123924 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

TkA08G164190

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA08G164190
LocationCM104805.1:20122314-20123924 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016114

LXL04_032307

MVA/MEP and isoprenoidPrenyl-donor metabolismMedium · score 6
Source ID-
LocationCM104805.1:20171877-20173499 +
EvidenceGOExpressionLocalizationPfamSwiss-Prot
Key evidenceGO:0016114

LXL04_032307

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source ID-
LocationCM104805.1:20171877-20173499 +
EvidenceGOExpressionLocalizationPfamSwiss-Prot
Key evidenceGO:0016114

TkA08G170700

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkA08G170700
LocationCM104805.1:21614998-21617777 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtCoexpression
Key evidenceGO:0016740

LXL04_032401

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source ID-
LocationCM104805.1:21793061-21796603 -
EvidenceGOExpressionLocalizationSwiss-ProtCoexpression
Key evidenceGO:0008299

TkA08G173390

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA08G173390
LocationCM104805.1:22434147-22437118 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010082 regulation of root meristem growth biological_process

TkA08G173400

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source IDTkA08G173400
LocationCM104805.1:22440538-22443336 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010053 root epidermal cell differentiation biological_process

LXL04_032501

Latex/root related candidatesLatex/root associated candidatesMedium · score 6
Source ID-
LocationCM104805.1:24117074-24120869 -
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidencego:0010078 maintenance of root meristem identity biological_process

TkAUNG016680

Rubber biosynthesisRubber biosynthesis candidatesMedium · score 6
Source IDTkAUNG016680;TkA08G189430
LocationCM104805.1:25800364-25802598 +
EvidenceGOExpressionLocalizationPfamSwiss-ProtPPICoexpression
Key evidenceGO:0016740

Evidence Boundary

Current results integrate annotation, GO/KEGG, homology, predicted localization, domains, expression/proteome and network evidence. High/Medium/Low indicates evidence density and consistency, not experimental validation.