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基因注释

展示当前基因的功能描述、GO/KEGG 注释及分物种同源证据。命中结果按查询版本、序列来源和比对证据分层显示。

示例 TkA01G624900 LXL04_000258 文献示例 LXL04_039733 TkAUNG001940

查询结果

下载当前结果

基因 IDLXL04_005054
当前查询版本OH1004
位置Chr01:153890884-153896764 (-)
描述Similar to ROS1: DNA glycosylase/AP lyase ROS1 (Arabidopsis thaliana OX%3D3702)
注释来源组装GCA_047496595.1_OSU_TarKok_2.0

功能注释来源：OH1004 · LXL04_005054 · GCA_047496595.1_OSU_TarKok_2.0。

当前查询返回来自 OH1004 注释条目的 20 条 GO 注释和 4 条 KEGG 基因交叉引用；只下载当前查询结果，不据此推断 KEGG 通路成员。

拟南芥 / 水稻参考基因与文献

文献对应拟南芥或水稻参考基因；橡胶草的功能关联来自当前参考组装的蛋白序列比对。

下载当前基因文献

拟南芥

参考基因 ID可能功能对应论文 / DOI
At2g36490 双功能 DNA 糖基化酶/裂解酶，可切除 5-甲基胞嘧啶 (5-meC) 和 5-羟甲基胞嘧啶 (5-hmeC)，留下一个嘧啶缺失 (AP) 位点，随后由裂解酶活性切割。
ROS1, a repressor of transcriptional gene silencing in Arabidopsis, encodes a DNA glycosylase/lyase.2002 · DOI: 10.1016/s0092-8674(02)01133-9
DEMETER and REPRESSOR OF SILENCING 1 encode 5-methylcytosine DNA glycosylases.2006 · DOI: 10.1073/pnas.0601109103
ROS1 5-methylcytosine DNA glycosylase is a slow-turnover catalyst that initiates DNA demethylation in a distributive fashion.2009 · DOI: 10.1093/nar/gkp390
Methylation-independent DNA binding modulates specificity of Repressor of Silencing 1 (ROS1) and facilitates demethylation in long substrates.2010 · DOI: 10.1074/jbc.m110.124578
DDM1 and ROS1 have a role in UV-B induced- and oxidative DNA damage in A. thaliana.2013 · DOI: 10.3389/fpls.2013.00420
AP endonucleases process 5-methylcytosine excision intermediates during active DNA demethylation in Arabidopsis.2014 · DOI: 10.1093/nar/gku834
The carboxy-terminal domain of ROS1 is essential for 5-methylcytosine DNA glycosylase activity.2014 · DOI: 10.1016/j.jmb.2014.09.010
UniProt: Q8LK56 参与基因印记的转录激活因子。 暂无已核实直接文献
At3g10010 潜在的转录激活因子，可能通过切割目标启动子发挥作用。 暂无已核实直接文献

水稻

参考基因 ID可能功能对应论文 / DOI
Os01g0218032 双功能DNA糖基化酶/裂解酶，可切除5-甲基胞嘧啶 (5-meC) 和5-羟甲基胞嘧啶 (5-hmeC)，产生一个嘧啶缺位(AP)位点，随后该位点由裂解酶活性切开（可能）。
A null mutation of ROS1a for DNA demethylation in rice is not transmittable to progeny.2012 · DOI: 10.1111/j.1365-313x.2012.05009.x
Mutations in the DNA demethylase OsROS1 result in a thickened aleurone and improved nutritional value in rice grains.2018 · DOI: 10.1073/pnas.1806304115
Os05g0445900 双功能 DNA 糖基化酶/裂解酶，可切除 5-甲基胞嘧啶 (5-meC) 和 5-羟甲基胞嘧啶 (5-hmeC)，留下一个嘧啶缺失 (AP) 位点，随后由裂解酶活性切割。
A 5-methylcytosine DNA glycosylase/lyase demethylates the retrotransposon Tos17 and promotes its transposition in rice.2011 · DOI: 10.1073/pnas.1112704108

GO / KEGG

以下 GO/KEGG 注释源自上述 OH1004 注释条目，保留原始同源转移证据及覆盖度；其来源物种范围与拟南芥/水稻直接比对表不同。

类型ID名称命名空间证据来源
GOGO:0006281DNA repair生物过程Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=54.088; 覆盖度=70.147; E 值=0.0; UniProt GO evidence=IMP:TAIRUniProtKB/Swiss-Prot DAT 2026 current_release
GOGO:0006284base-excision repair生物过程Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=54.088; 覆盖度=70.147; E 值=0.0; UniProt GO evidence=IEA:InterProUniProtKB/Swiss-Prot DAT 2026 current_release
GOGO:0006351DNA-templated transcription生物过程Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=54.088; 覆盖度=70.147; E 值=0.0; UniProt GO evidence=IEA:UniProtKB-KWUniProtKB/Swiss-Prot DAT 2026 current_release
GOGO:0009793embryo development ending in seed dormancy生物过程Swiss-Prot reviewed 同源转移; 命中排序=4; 一致性=66.549; 覆盖度=41.765; E 值=0.0; UniProt GO evidence=IMP:TAIRUniProtKB/Swiss-Prot DAT 2026 current_release
GOGO:0040029epigenetic regulation of gene expression生物过程Swiss-Prot reviewed 同源转移; 命中排序=2; 一致性=65.913; 覆盖度=42.279; E 值=0.0; UniProt GO evidence=IDA:UniProtKBUniProtKB/Swiss-Prot DAT 2026 current_release
GOGO:0050832defense response to fungus生物过程Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=54.088; 覆盖度=70.147; E 值=0.0; UniProt GO evidence=IMP:TAIRUniProtKB/Swiss-Prot DAT 2026 current_release
GOGO:0141044epigenetic programming in the endosperm生物过程Swiss-Prot reviewed 同源转移; 命中排序=4; 一致性=66.549; 覆盖度=41.765; E 值=0.0; UniProt GO evidence=IMP:TAIRUniProtKB/Swiss-Prot DAT 2026 current_release
GOGO:0141166chromosomal 5-methylcytosine DNA demethylation pathway生物过程Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=54.088; 覆盖度=70.147; E 值=0.0; UniProt GO evidence=IEA:InterProUniProtKB/Swiss-Prot DAT 2026 current_release
GOGO:0005634nucleus细胞组分Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=54.088; 覆盖度=70.147; E 值=0.0; UniProt GO evidence=IDA:TAIRUniProtKB/Swiss-Prot DAT 2026 current_release
GOGO:0005730nucleolus细胞组分Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=54.088; 覆盖度=70.147; E 值=0.0; UniProt GO evidence=IEA:UniProtKB-SubCellUniProtKB/Swiss-Prot DAT 2026 current_release
GOGO:0043078polar nucleus细胞组分Swiss-Prot reviewed 同源转移; 命中排序=4; 一致性=66.549; 覆盖度=41.765; E 值=0.0; UniProt GO evidence=IDA:TAIRUniProtKB/Swiss-Prot DAT 2026 current_release
GOGO:0003677DNA binding分子功能Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=54.088; 覆盖度=70.147; E 值=0.0; UniProt GO evidence=IEA:UniProtKB-KWUniProtKB/Swiss-Prot DAT 2026 current_release
GOGO:0003906DNA-(apurinic or apyrimidinic site) endonuclease activity分子功能Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=54.088; 覆盖度=70.147; E 值=0.0; UniProt GO evidence=IDA:TAIRUniProtKB/Swiss-Prot DAT 2026 current_release
GOGO:0019104DNA N-glycosylase activity分子功能Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=54.088; 覆盖度=70.147; E 值=0.0; UniProt GO evidence=IDA:TAIRUniProtKB/Swiss-Prot DAT 2026 current_release
GOGO:0032183SUMO binding分子功能Swiss-Prot reviewed 同源转移; 命中排序=4; 一致性=66.549; 覆盖度=41.765; E 值=0.0; UniProt GO evidence=IPI:TAIRUniProtKB/Swiss-Prot DAT 2026 current_release
GOGO:0035514DNA demethylase activity分子功能Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=54.088; 覆盖度=70.147; E 值=0.0; UniProt GO evidence=IDA:TAIRUniProtKB/Swiss-Prot DAT 2026 current_release
GOGO:0046872metal ion binding分子功能Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=54.088; 覆盖度=70.147; E 值=0.0; UniProt GO evidence=IEA:UniProtKB-KWUniProtKB/Swiss-Prot DAT 2026 current_release
GOGO:00515394 iron, 4 sulfur cluster binding分子功能Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=54.088; 覆盖度=70.147; E 值=0.0; UniProt GO evidence=IEA:UniProtKB-KWUniProtKB/Swiss-Prot DAT 2026 current_release
GOGO:0051747cytosine C-5 DNA demethylase activity分子功能Swiss-Prot reviewed 同源转移; 命中排序=2; 一致性=65.913; 覆盖度=42.279; E 值=0.0; UniProt GO evidence=IDA:UniProtKBUniProtKB/Swiss-Prot DAT 2026 current_release
GOGO:0140078class I DNA-(apurinic or apyrimidinic site) endonuclease activity分子功能Swiss-Prot reviewed 同源转移; 命中排序=1; 一致性=54.088; 覆盖度=70.147; E 值=0.0; UniProt GO evidence=IEA:UniProtKB-ECUniProtKB/Swiss-Prot DAT 2026 current_release
KEGGath:AT2G36490KEGG gene cross-reference from reviewed UniProt hit; pathway name pendingSwiss-Prot reviewed 同源转移; 命中排序=1; 一致性=54.088; 覆盖度=70.147; E 值=0.0UniProtKB/Swiss-Prot DAT 2026 current_release
KEGGath:AT5G04560KEGG gene cross-reference from reviewed UniProt hit; pathway name pendingSwiss-Prot reviewed 同源转移; 命中排序=4; 一致性=66.549; 覆盖度=41.765; E 值=0.0UniProtKB/Swiss-Prot DAT 2026 current_release
KEGGdosa:Os01g0217900KEGG gene cross-reference from reviewed UniProt hit; pathway name pendingSwiss-Prot reviewed 同源转移; 命中排序=2; 一致性=65.913; 覆盖度=42.279; E 值=0.0UniProtKB/Swiss-Prot DAT 2026 current_release
KEGGosa:9271145KEGG gene cross-reference from reviewed UniProt hit; pathway name pendingSwiss-Prot reviewed 同源转移; 命中排序=2; 一致性=65.913; 覆盖度=42.279; E 值=0.0UniProtKB/Swiss-Prot DAT 2026 current_release