query	query_gene_id	query_protein_id	source_reference	hit_rank	swissprot_acc	swissprot_entry	database_section	target_gene_id	description	organism	homolog_gene_name	percent_identity	alignment_length	query_coverage	evalue	bitscore	confidence	evidence_type	source_db	reference_gene_id	reference_function_zh	reference_function_en	reference_papers_json
LXL04_030734	gene-LXL04_030734	KAL4566614.1	OH-1004	1	Q9FML2	HDA6_ARATH	Swiss-Prot		Histone deacetylase 6 OS=Arabidopsis thaliana OX=3702 GN=HDA6 PE=1 SV=1	Arabidopsis thaliana	HDA6	77.706	462	98.081	0.0	751.0	strong_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At5g63110	催化核心组蛋白H2A、H2B、H3和H4的N端赖氨酸残基去乙酰化。	Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4).	"[{""pmid"":""11340181"",""title"":""Identification of Arabidopsis histone deacetylase HDA6 mutants that affect transgene expression."",""doi"":""10.1105/tpc.13.5.1047"",""url"":""https://pubmed.ncbi.nlm.nih.gov/11340181/"",""year"":""2001"",""journal"":""The Plant cell"",""authors"":""Murfett J, Wang XJ, Hagen G, Guilfoyle TJ."",""matched_aliases"":[""AtHDA6"",""HDA6""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""12486004"",""title"":""HDA6, a putative histone deacetylase needed to enhance DNA methylation induced by double-stranded RNA."",""doi"":""10.1093/emboj/cdf663"",""url"":""https://pubmed.ncbi.nlm.nih.gov/12486004/"",""year"":""2002"",""journal"":""The EMBO journal"",""authors"":""Aufsatz W, Mette MF, van der Winden J, Matzke M, Matzke AJ."",""matched_aliases"":[""HDA6""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""15037732"",""title"":""Arabidopsis histone deacetylase HDA6 is required for maintenance of transcriptional gene silencing and determines nuclear organization of rDNA repeats."",""doi"":""10.1105/tpc.018754"",""url"":""https://pubmed.ncbi.nlm.nih.gov/15037732/"",""year"":""2004"",""journal"":""The Plant cell"",""authors"":""Probst AV, Fagard M, Proux F, Mourrain P, Boutet S, Earley K, Lawrence RJ, Pikaard CS, Murfett J, Furner I, Vaucheret H, Mittelsten Scheid O."",""matched_aliases"":[""HDA6""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""16648464"",""title"":""Erasure of histone acetylation by Arabidopsis HDA6 mediates large-scale gene silencing in nucleolar dominance."",""doi"":""10.1101/gad.1417706"",""url"":""https://pubmed.ncbi.nlm.nih.gov/16648464/"",""year"":""2006"",""journal"":""Genes & development"",""authors"":""Earley K, Lawrence RJ, Pontes O, Reuther R, Enciso AJ, Silva M, Neves N, Gross M, Viegas W, Pikaard CS."",""matched_aliases"":[""HDA6""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""21398257"",""title"":""HISTONE DEACETYLASE6 interacts with FLOWERING LOCUS D and regulates flowering in Arabidopsis."",""doi"":""10.1104/pp.111.174417"",""url"":""https://pubmed.ncbi.nlm.nih.gov/21398257/"",""year"":""2011"",""journal"":""Plant physiology"",""authors"":""Yu CW, Liu X, Luo M, Chen C, Lin X, Tian G, Lu Q, Cui Y, Wu K."",""matched_aliases"":[""HDA6""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""23271976"",""title"":""Histone deacetylase HDA6 is functionally associated with AS1 in repression of KNOX genes in arabidopsis."",""doi"":""10.1371/journal.pgen.1003114"",""url"":""https://pubmed.ncbi.nlm.nih.gov/23271976/"",""year"":""2012"",""journal"":""PLoS genetics"",""authors"":""Luo M, Yu CW, Chen FF, Zhao L, Tian G, Liu X, Cui Y, Yang JY, Wu K."",""matched_aliases"":[""HDA6""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""25922987"",""title"":""Regulation of flowering time by the histone deacetylase HDA5 in Arabidopsis."",""doi"":""10.1111/tpj.12868"",""url"":""https://pubmed.ncbi.nlm.nih.gov/25922987/"",""year"":""2015"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""Luo M, Tai R, Yu CW, Yang S, Chen CY, Lin WD, Schmidt W, Wu K."",""matched_aliases"":[""HDA6""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""41036628"",""title"":""The arabidopsis GyraseB3 contributes to transposon silencing by promoting histone deacetylation."",""doi"":""10.1093/nar/gkaf985"",""url"":""https://pubmed.ncbi.nlm.nih.gov/41036628/"",""year"":""2025"",""journal"":""Nucleic acids research"",""authors"":""Gy I; Beaubiat S; Bouché N"",""matched_aliases"":[""HDA6""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false}]"
LXL04_030734	gene-LXL04_030734	KAL4566614.1	OH-1004	2	O22446	HDA19_ARATH	Swiss-Prot		Histone deacetylase 19 OS=Arabidopsis thaliana OX=3702 GN=HDA19 PE=1 SV=2	Arabidopsis thaliana	HDA19	70.803	411	87.207	0.0	605.0	strong_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At4g38130	催化核心组蛋白H2A、H2B、H3和H4的N端赖氨酸残基去乙酰化。	Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4).	"[{""pmid"":""11117260"",""title"":""Functional analysis of a RPD3 histone deacetylase homologue in Arabidopsis thaliana."",""doi"":""10.1023/a:1006498413543"",""url"":""https://pubmed.ncbi.nlm.nih.gov/11117260/"",""year"":""2000"",""journal"":""Plant molecular biology"",""authors"":""Wu K, Malik K, Tian L, Brown D, Miki B."",""matched_aliases"":[""AtRPD3A""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""15749761"",""title"":""HISTONE DEACETYLASE19 is involved in jasmonic acid and ethylene signaling of pathogen response in Arabidopsis."",""doi"":""10.1105/tpc.104.028514"",""url"":""https://pubmed.ncbi.nlm.nih.gov/15749761/"",""year"":""2005"",""journal"":""The Plant cell"",""authors"":""Zhou C, Zhang L, Duan J, Miki B, Wu K."",""matched_aliases"":[""AtRPD3A"",""HDA19""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""16699543"",""title"":""Arabidopsis thaliana histone deacetylase 1 (AtHD1) is localized in euchromatic regions and demonstrates histone deacetylase activity in vitro."",""doi"":""10.1038/sj.cr.7310059"",""url"":""https://pubmed.ncbi.nlm.nih.gov/16699543/"",""year"":""2006"",""journal"":""Cell research"",""authors"":""Fong PM, Tian L, Chen ZJ."",""matched_aliases"":[""AtHDA19""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""23034631"",""title"":""APETALA2 negatively regulates multiple floral organ identity genes in Arabidopsis by recruiting the co-repressor TOPLESS and the histone deacetylase HDA19."",""doi"":""10.1242/dev.085407"",""url"":""https://pubmed.ncbi.nlm.nih.gov/23034631/"",""year"":""2012"",""journal"":""Development (Cambridge, England)"",""authors"":""Krogan NT, Hogan K, Long JA."",""matched_aliases"":[""HDA19""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""29018096"",""title"":""The Distinct Roles of Class I and II RPD3-Like Histone Deacetylases in Salinity Stress Response."",""doi"":""10.1104/pp.17.01332"",""url"":""https://pubmed.ncbi.nlm.nih.gov/29018096/"",""year"":""2017"",""journal"":""Plant physiology"",""authors"":""Ueda M, Matsui A, Tanaka M, Nakamura T, Abe T, Sako K, Sasaki T, Kim JM, Ito A, Nishino N, Shimada H, Yoshida M, Seki M."",""matched_aliases"":[""HDA19""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"
LXL04_030734	gene-LXL04_030734	KAL4566614.1	OH-1004	3	Q7Y0Y8	HDAC1_ORYSJ	Swiss-Prot		Histone deacetylase 1 OS=Oryza sativa subsp. japonica OX=39947 GN=HDAC1 PE=1 SV=1	Oryza sativa subsp. japonica	HDAC1	64.378	466	98.081	0.0	592.0	strong_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	Os06g0583400	催化核心组蛋白H2A、H2B、H3和H4的N端赖氨酸残基去乙酰化。	Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4).	"[{""pmid"":""12581311"",""title"":""Structure and expression of the rice class-I type histone deacetylase genes OsHDAC1-3: OsHDAC1 overexpression in transgenic plants leads to increased growth rate and altered architecture."",""doi"":""10.1046/j.1365-313x.2003.01650.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/12581311/"",""year"":""2003"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""Jang IC; Pahk YM; Song SI; Kwon HJ; Nahm BH; Kim JK"",""matched_aliases"":[""HDAC1"",""OsHDAC1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""19453457"",""title"":""The histone deacetylase OsHDAC1 epigenetically regulates the OsNAC6 gene that controls seedling root growth in rice."",""doi"":""10.1111/j.1365-313x.2009.03908.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/19453457/"",""year"":""2009"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""Chung PJ, Kim YS, Jeong JS, Park SH, Nahm BH, Kim JK."",""matched_aliases"":[""OsHDAC1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""27468891"",""title"":""MODD Mediates Deactivation and Degradation of OsbZIP46 to Negatively Regulate ABA Signaling and Drought Resistance in Rice."",""doi"":""10.1105/tpc.16.00171"",""url"":""https://pubmed.ncbi.nlm.nih.gov/27468891/"",""year"":""2016"",""journal"":""The Plant cell"",""authors"":""Tang N, Ma S, Zong W, Yang N, Lv Y, Yan C, Guo Z, Li J, Li X, Xiang Y, Song H, Xiao J, Li X, Xiong L."",""matched_aliases"":[""HDA702""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"