query	query_gene_id	query_protein_id	source_reference	hit_rank	swissprot_acc	swissprot_entry	database_section	target_gene_id	description	organism	homolog_gene_name	percent_identity	alignment_length	query_coverage	evalue	bitscore	confidence	evidence_type	source_db	reference_gene_id	reference_function_zh	reference_function_en	reference_papers_json
TkAUNG064970	TkAUNG064970	TkAUNG064970.1	TK1151	1	Q84JU6	HOS1_ARATH	Swiss-Prot		sp|Q84JU6|HOS1_ARATH E3 ubiquitin-protein ligase HOS1	Arabidopsis thaliana	HOS1	48.2	407	78.326	4.27e-116	365.0	Medium	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	At2g39810	E3泛素蛋白连接酶，介导转录因子ICE1的泛素化及随后的蛋白酶体降解。	E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of the transcription factor ICE1.	"[{""pmid"":""16702557"",""title"":""The negative regulator of plant cold responses, HOS1, is a RING E3 ligase that mediates the ubiquitination and degradation of ICE1."",""doi"":""10.1073/pnas.0602874103"",""url"":""https://pubmed.ncbi.nlm.nih.gov/16702557/"",""year"":""2006"",""journal"":""Proceedings of the National Academy of Sciences of the United States of America"",""authors"":""Dong CH; Agarwal M; Zhang Y; Xie Q; Zhu JK"",""matched_aliases"":[""HOS1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""22960247"",""title"":""The E3 ubiquitin ligase HOS1 regulates low ambient temperature-responsive flowering in Arabidopsis thaliana."",""doi"":""10.1093/pcp/pcs123"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22960247/"",""year"":""2012"",""journal"":""Plant & cell physiology"",""authors"":""Lee JH; Kim JJ; Kim SH; Cho HJ; Kim J; Ahn JH"",""matched_aliases"":[""HOS1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false}]"