query	query_gene_id	query_protein_id	source_reference	hit_rank	swissprot_acc	swissprot_entry	database_section	target_gene_id	description	organism	homolog_gene_name	percent_identity	alignment_length	query_coverage	evalue	bitscore	confidence	evidence_type	source_db	reference_gene_id	reference_function_zh	reference_function_en	reference_papers_json
TkA08G394890	TkA08G394890	TkA08G394890.1	TK1151	1	Q39011	KSG7_ARATH	Swiss-Prot		sp|Q39011|KSG7_ARATH Shaggy-related protein kinase eta	Arabidopsis thaliana	ASK7	86.4	369	99.461	1.11e-245	673.0	High	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	At4g18710	油菜素甾醇信号转导途径的负调节因子，对植物生长很重要。	Negative regulator in brassinosteroid signal transduction pathway important for plant growth.	"[{""pmid"":""11847343"",""title"":""Regulation of brassinosteroid signaling by a GSK3/SHAGGY-like kinase."",""doi"":""10.1126/science.1065769"",""url"":""https://pubmed.ncbi.nlm.nih.gov/11847343/"",""year"":""2002"",""journal"":""Science (New York, N.Y.)"",""authors"":""Li J, Nam KH."",""matched_aliases"":[""BIN2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""12114546"",""title"":""The GSK3-like kinase BIN2 phosphorylates and destabilizes BZR1, a positive regulator of the brassinosteroid signaling pathway in Arabidopsis."",""doi"":""10.1073/pnas.152342599"",""url"":""https://pubmed.ncbi.nlm.nih.gov/12114546/"",""year"":""2002"",""journal"":""Proceedings of the National Academy of Sciences of the United States of America"",""authors"":""He JX, Gendron JM, Yang Y, Li J, Wang ZY."",""matched_aliases"":[""BIN2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""12427989"",""title"":""Two putative BIN2 substrates are nuclear components of brassinosteroid signaling."",""doi"":""10.1104/pp.102.010918"",""url"":""https://pubmed.ncbi.nlm.nih.gov/12427989/"",""year"":""2002"",""journal"":""Plant physiology"",""authors"":""Zhao J, Peng P, Schmitz RJ, Decker AD, Tax FE, Li J."",""matched_aliases"":[""BIN2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""22307275"",""title"":""Brassinosteroid regulates stomatal development by GSK3-mediated inhibition of a MAPK pathway."",""doi"":""10.1038/nature10794"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22307275/"",""year"":""2012"",""journal"":""Nature"",""authors"":""Kim TW, Michniewicz M, Bergmann DC, Wang ZY."",""matched_aliases"":[""BIN2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""22466366"",""title"":""SPEECHLESS integrates brassinosteroid and stomata signalling pathways."",""doi"":""10.1038/ncb2471"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22466366/"",""year"":""2012"",""journal"":""Nature cell biology"",""authors"":""Gudesblat GE, Schneider-Pizoń J, Betti C, Mayerhofer J, Vanhoutte I, van Dongen W, Boeren S, Zhiponova M, de Vries S, Jonak C, Russinova E."",""matched_aliases"":[""BIN2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""23341468"",""title"":""Brassinosteroid-regulated GSK3/Shaggy-like kinases phosphorylate mitogen-activated protein (MAP) kinase kinases, which control stomata development in Arabidopsis thaliana."",""doi"":""10.1074/jbc.m112.384453"",""url"":""https://pubmed.ncbi.nlm.nih.gov/23341468/"",""year"":""2013"",""journal"":""The Journal of biological chemistry"",""authors"":""Khan M, Rozhon W, Bigeard J, Pflieger D, Husar S, Pitzschke A, Teige M, Jonak C, Hirt H, Poppenberger B."",""matched_aliases"":[""BIN2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""23496207"",""title"":""BSKs are partially redundant positive regulators of brassinosteroid signaling in Arabidopsis."",""doi"":""10.1111/tpj.12175"",""url"":""https://pubmed.ncbi.nlm.nih.gov/23496207/"",""year"":""2013"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""Sreeramulu S, Mostizky Y, Sunitha S, Shani E, Nahum H, Salomon D, Hayun LB, Gruetter C, Rauh D, Ori N, Sessa G."",""matched_aliases"":[""BIN2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""30429609"",""title"":""POLAR-guided signalling complex assembly and localization drive asymmetric cell division."",""doi"":""10.1038/s41586-018-0714-x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/30429609/"",""year"":""2018"",""journal"":""Nature"",""authors"":""Houbaert A, Zhang C, Tiwari M, Wang K, de Marcos Serrano A, Savatin DV, Urs MJ, Zhiponova MK, Gudesblat GE, Vanhoutte I, Eeckhout D, Boeren S, Karimi M, Betti C, Jacobs T, Fenoll C, Mena M, de Vries S, De Jaeger G, Russinova E."",""matched_aliases"":[""BIN2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"
TkA08G394890	TkA08G394890	TkA08G394890.1	TK1151	2	Q39010	KSG6_ARATH	Swiss-Prot		sp|Q39010|KSG6_ARATH Shaggy-related protein kinase zeta	Arabidopsis thaliana	ASK6	86.0	365	98.383	3.47e-243	668.0	High	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	At2g30980	可能介导细胞外信号以调节分化细胞中的转录。	May mediate extracellular signals to regulate transcription in differentiating cells.	[]
TkA08G394890	TkA08G394890	TkA08G394890.1	TK1151	3	Q39012	KSG9_ARATH	Swiss-Prot		sp|Q39012|KSG9_ARATH Shaggy-related protein kinase iota	Arabidopsis thaliana	ASK9	84.8	369	98.922	7.9e-241	662.0	High	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	At1g06390	体外磷酸化 BSK1、BSK3、BSK5、BSK6、BSK8 和 BSK11。	Phosphorylates BSK1, BSK3, BSK5, BSK6, BSK8 and BSK11 in vitro.	"[{""pmid"":""23496207"",""title"":""BSKs are partially redundant positive regulators of brassinosteroid signaling in Arabidopsis."",""doi"":""10.1111/tpj.12175"",""url"":""https://pubmed.ncbi.nlm.nih.gov/23496207/"",""year"":""2013"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""Sreeramulu S, Mostizky Y, Sunitha S, Shani E, Nahum H, Salomon D, Hayun LB, Gruetter C, Rauh D, Ori N, Sessa G."",""matched_aliases"":[""BIL2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"
TkA08G394890	TkA08G394890	TkA08G394890.1	TK1151	4	Q9LWN0	GSK1_ORYSJ	Swiss-Prot		sp|Q9LWN0|GSK1_ORYSJ Shaggy-related protein kinase GSK1	Oryza sativa subsp. japonica	GSK1	85.1	356	95.957	1.19e-235	649.0	High	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	Os01g0205700	可能的丝氨酸-苏氨酸激酶，可能在花发育过程中充当油菜素甾醇 信号传导的负调节因子。	Probable serine-threonine kinase that may act as a negative regulator of brassinosteroid (BR) signaling during flower development.	"[{""pmid"":""17690841"",""title"":""T-DNA tagged knockout mutation of rice OsGSK1, an orthologue of Arabidopsis BIN2, with enhanced tolerance to various abiotic stresses."",""doi"":""10.1007/s11103-007-9213-4"",""url"":""https://pubmed.ncbi.nlm.nih.gov/17690841/"",""year"":""2007"",""journal"":""Plant molecular biology"",""authors"":""Koh S, Lee SC, Kim MK, Koh JH, Lee S, An G, Choe S, Kim SR."",""matched_aliases"":[""OsGSK1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"
TkA08G394890	TkA08G394890	TkA08G394890.1	TK1151	5	Q60EZ2	GSK2_ORYSJ	Swiss-Prot		sp|Q60EZ2|GSK2_ORYSJ Shaggy-related protein kinase GSK2	Oryza sativa subsp. japonica	GSK2	85.7	356	95.957	2e-235	648.0	High	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	Os05g0207500	丝氨酸-苏氨酸激酶，充当油菜素甾醇 信号传导的负调节因子。	Serine-threonine kinase that acts as a negative regulator of brassinosteroid (BR) signaling.	"[{""pmid"":""22685166"",""title"":""DWARF AND LOW-TILLERING acts as a direct downstream target of a GSK3/SHAGGY-like kinase to mediate brassinosteroid responses in rice."",""doi"":""10.1105/tpc.112.097394"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22685166/"",""year"":""2012"",""journal"":""The Plant cell"",""authors"":""Tong H, Liu L, Jin Y, Du L, Yin Y, Qian Q, Zhu L, Chu C."",""matched_aliases"":[""GSK2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""27332964"",""title"":""OVATE Family Protein 8 Positively Mediates Brassinosteroid Signaling through Interacting with the GSK3-like Kinase in Rice."",""doi"":""10.1371/journal.pgen.1006118"",""url"":""https://pubmed.ncbi.nlm.nih.gov/27332964/"",""year"":""2016"",""journal"":""PLoS genetics"",""authors"":""Yang C, Shen W, He Y, Tian Z, Li J."",""matched_aliases"":[""OsGSK2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""30920691"",""title"":""OsBZR1 turnover mediated by OsSK22-regulated U-box E3 ligase OsPUB24 in rice BR response."",""doi"":""10.1111/tpj.14332"",""url"":""https://pubmed.ncbi.nlm.nih.gov/30920691/"",""year"":""2019"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""Min HJ, Cui LH, Oh TR, Kim JH, Kim TW, Kim WT."",""matched_aliases"":[""OsSK22""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"