query	query_gene_id	query_protein_id	source_reference	hit_rank	swissprot_acc	swissprot_entry	database_section	target_gene_id	description	organism	homolog_gene_name	percent_identity	alignment_length	query_coverage	evalue	bitscore	confidence	evidence_type	source_db	reference_gene_id	reference_function_zh	reference_function_en	reference_papers_json
TkA07G107060	TkA07G107060	TkA07G107060.1	TK1151	1	Q9SPL2	CIP8_ARATH	Swiss-Prot		sp|Q9SPL2|CIP8_ARATH E3 ubiquitin-protein ligase CIP8	Arabidopsis thaliana	CIP8	48.0	50	45.455	6.34e-12	63.5	Low	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	At5g64920	E3 泛素蛋白连接酶，介导靶蛋白的泛素化和随后的蛋白酶体降解。	E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins.	"[{""pmid"":""10488108"",""title"":""The RING finger motif of photomorphogenic repressor COP1 specifically interacts with the RING-H2 motif of a novel Arabidopsis protein."",""doi"":""10.1074/jbc.274.39.27674"",""url"":""https://pubmed.ncbi.nlm.nih.gov/10488108/"",""year"":""1999"",""journal"":""The Journal of biological chemistry"",""authors"":""Torii KU, Stoop-Myer CD, Okamoto H, Coleman JE, Matsui M, Deng XW."",""matched_aliases"":[""CIP8""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""12028569"",""title"":""Biochemical evidence for ubiquitin ligase activity of the Arabidopsis COP1 interacting protein 8 (CIP8)."",""doi"":""10.1046/j.1365-313x.2002.01298.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/12028569/"",""year"":""2002"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""Hardtke CS, Okamoto H, Stoop-Myer C, Deng XW."",""matched_aliases"":[""CIP8""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"
TkA07G107060	TkA07G107060	TkA07G107060.1	TK1151	2	Q9SNB6	RDUF1_ARATH	Swiss-Prot		sp|Q9SNB6|RDUF1_ARATH E3 ubiquitin-protein ligase RDUF1	Arabidopsis thaliana	RDUF1	49.0	49	44.545	2.5e-11	62.0	Low	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	At3g46620	参与正向调控脱落酸依赖干旱胁迫响应的E3泛素蛋白连接酶。	E3 ubiquitin-protein ligase involved in the positive regulation of abscisic acid-dependent drought stress responses.	"[{""pmid"":""22405823"",""title"":""Suppression of Arabidopsis RING-DUF1117 E3 ubiquitin ligases, AtRDUF1 and AtRDUF2, reduces tolerance to ABA-mediated drought stress."",""doi"":""10.1016/j.bbrc.2012.02.131"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22405823/"",""year"":""2012"",""journal"":""Biochemical and biophysical research communications"",""authors"":""Kim SJ; Ryu MY; Kim WT"",""matched_aliases"":[""At3g46620"",""AtRDUF1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""23951086"",""title"":""The E3 ligase AtRDUF1 positively regulates salt stress responses in Arabidopsis thaliana."",""doi"":""10.1371/journal.pone.0071078"",""url"":""https://pubmed.ncbi.nlm.nih.gov/23951086/"",""year"":""2013"",""journal"":""PloS one"",""authors"":""Li J; Han Y; Zhao Q; Li C; Xie Q; Chong K; Xu Y"",""matched_aliases"":[""AtRDUF1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false}]"
TkA07G107060	TkA07G107060	TkA07G107060.1	TK1151	3	Q940T5	RDUF2_ARATH	Swiss-Prot		sp|Q940T5|RDUF2_ARATH E3 ubiquitin-protein ligase RDUF2	Arabidopsis thaliana	DURF2	42.9	49	44.545	1.06e-09	57.4	Low	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	At5g59550	参与正向调控脱落酸依赖干旱胁迫响应的E3泛素蛋白连接酶。	E3 ubiquitin-protein ligase involved in the positive regulation of abscisic acid-dependent drought stress responses.	"[{""pmid"":""22405823"",""title"":""Suppression of Arabidopsis RING-DUF1117 E3 ubiquitin ligases, AtRDUF1 and AtRDUF2, reduces tolerance to ABA-mediated drought stress."",""doi"":""10.1016/j.bbrc.2012.02.131"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22405823/"",""year"":""2012"",""journal"":""Biochemical and biophysical research communications"",""authors"":""Kim SJ; Ryu MY; Kim WT"",""matched_aliases"":[""At5g59550""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false}]"
TkA07G107060	TkA07G107060	TkA07G107060.1	TK1151	4	Q8L649	BB_ARATH	Swiss-Prot		sp|Q8L649|BB_ARATH E3 ubiquitin-protein ligase BIG BROTHER	Arabidopsis thaliana	BB	36.5	52	44.545	3.32e-08	52.8	Low	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	At3g63530	E3 泛素蛋白连接酶，以剂量依赖性方式限制器官大小，可能还限制种子大小。	E3 ubiquitin-protein ligase that limits organ size, and possibly seed size, in a dose-dependent manner.	"[{""pmid"":""28003326"",""title"":""Forever Young: The Role of Ubiquitin Receptor DA1 and E3 Ligase BIG BROTHER in Controlling Leaf Growth and Development."",""doi"":""10.1104/pp.16.01410"",""url"":""https://pubmed.ncbi.nlm.nih.gov/28003326/"",""year"":""2017"",""journal"":""Plant physiology"",""authors"":""Vanhaeren H, Nam YJ, De Milde L, Chae E, Storme V, Weigel D, Gonzalez N, Inzé D."",""matched_aliases"":[""EOD1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"