query	query_gene_id	query_protein_id	source_reference	hit_rank	swissprot_acc	swissprot_entry	database_section	target_gene_id	description	organism	homolog_gene_name	percent_identity	alignment_length	query_coverage	evalue	bitscore	confidence	evidence_type	source_db	reference_gene_id	reference_function_zh	reference_function_en	reference_papers_json
TkA04G401470	TkA04G401470	TkA04G401470.1	TK1151	1	Q9ZVP5	M3K18_ARATH	Swiss-Prot		sp|Q9ZVP5|M3K18_ARATH Mitogen-activated protein kinase kinase kinase 18	Arabidopsis thaliana	MAPKKK18	51.5	301	76.658	3.73e-99	300.0	High	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	At1g05100	脱落酸 信号通路的组成部分，在非生物胁迫下充当 ABA 信号转导器。	Component of the abscisic acid (ABA) signaling pathway that acts as ABA signal transducer in the context of abiotic stresses.	"[{""pmid"":""25680457"",""title"":""An abscisic acid inducible Arabidopsis MAPKKK, MAPKKK18 regulates leaf senescence via its kinase activity."",""doi"":""10.1007/s11103-015-0295-0"",""url"":""https://pubmed.ncbi.nlm.nih.gov/25680457/"",""year"":""2015"",""journal"":""Plant molecular biology"",""authors"":""Matsuoka D, Yasufuku T, Furuya T, Nanmori T."",""matched_aliases"":[""MAPKKK18""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""26443375"",""title"":""Arabidopsis ABA-Activated Kinase MAPKKK18 is Regulated by Protein Phosphatase 2C ABI1 and the Ubiquitin-Proteasome Pathway."",""doi"":""10.1093/pcp/pcv146"",""url"":""https://pubmed.ncbi.nlm.nih.gov/26443375/"",""year"":""2015"",""journal"":""Plant & cell physiology"",""authors"":""Mitula F, Tajdel M, Cieśla A, Kasprowicz-Maluśki A, Kulik A, Babula-Skowrońska D, Michalak M, Dobrowolska G, Sadowski J, Ludwików A."",""matched_aliases"":[""MAPKKK18""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"
TkA04G401470	TkA04G401470	TkA04G401470.1	TK1151	2	O80888	M3K17_ARATH	Swiss-Prot		sp|O80888|M3K17_ARATH Mitogen-activated protein kinase kinase kinase 17	Arabidopsis thaliana	MAPKKK17	51.7	294	75.862	3.45e-97	296.0	High	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	At2g32510	脱落酸（ABA）信号通路的组成部分，在非生物胁迫情况下可能作为ABA信号转导子。	Component of the abscisic acid (ABA) signaling pathway that may act as ABA signal transducer in the context of abiotic stresses.	[]
TkA04G401470	TkA04G401470	TkA04G401470.1	TK1151	3	Q9SND6	M3K20_ARATH	Swiss-Prot		sp|Q9SND6|M3K20_ARATH Mitogen-activated protein kinase kinase kinase 20	Arabidopsis thaliana	MAPKKK20	37.9	306	75.066	2.26e-55	188.0	Medium	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	At3g50310	丝裂原活化蛋白激酶激酶 (MAPKK)，可磷酸化 MKK3 和 MPK18 并调控两个分别与根部微管功能相关的信号通路。	Mitogen-activated protein kinase kinase (MAPKK) that phosphorylates both MKK3 and MPK18 and regulate two separate signaling pathways involved in root microtubule functions.	"[{""pmid"":""21969089"",""title"":""Arabidopsis MKKK20 is involved in osmotic stress response via regulation of MPK6 activity."",""doi"":""10.1007/s00299-011-1157-0"",""url"":""https://pubmed.ncbi.nlm.nih.gov/21969089/"",""year"":""2012"",""journal"":""Plant cell reports"",""authors"":""Kim JM; Woo DH; Kim SH; Lee SY; Park HY; Seok HY; Chung WS; Moon YH"",""matched_aliases"":[""MKKK20""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""27913741"",""title"":""AIK1, A Mitogen-Activated Protein Kinase, Modulates Abscisic Acid Responses through the MKK5-MPK6 Kinase Cascade."",""doi"":""10.1104/pp.16.01386"",""url"":""https://pubmed.ncbi.nlm.nih.gov/27913741/"",""year"":""2017"",""journal"":""Plant physiology"",""authors"":""Li K, Yang F, Zhang G, Song S, Li Y, Ren D, Miao Y, Song CP."",""matched_aliases"":[""AIK1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""28848569"",""title"":""The  Arabidopsis  Mitogen-Activated Protein Kinase Kinase Kinase 20 (MKKK20) Acts Upstream of MKK3 and MPK18 in Two Separate Signaling Pathways Involved in Root Microtubule Functions."",""doi"":""10.3389/fpls.2017.01352"",""url"":""https://pubmed.ncbi.nlm.nih.gov/28848569/"",""year"":""2017"",""journal"":""Frontiers in plant science"",""authors"":""Benhamman R, Bai F, Drory SB, Loubert-Hudon A, Ellis B, Matton DP."",""matched_aliases"":[""MKKK20""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"
TkA04G401470	TkA04G401470	TkA04G401470.1	TK1151	5	Q9FZ36	M3K2_ARATH	Swiss-Prot		sp|Q9FZ36|M3K2_ARATH Mitogen-activated protein kinase kinase kinase 2	Arabidopsis thaliana	ANP2	36.3	314	77.719	6.69e-47	172.0	Medium	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	At1g54960	通过调控MAP65-1等微管相关蛋白的磷酸化状态，参与皮层微管的组织和稳定。	Involved in cortical microtubules organization and stabilization by regulating the phosphorylation state of microtubule- associated proteins such as MAP65-1.	"[{""pmid"":""20215588"",""title"":""Arabidopsis homologs of nucleus- and phragmoplast-localized kinase 2 and 3 and mitogen-activated protein kinase 4 are essential for microtubule organization."",""doi"":""10.1105/tpc.109.071746"",""url"":""https://pubmed.ncbi.nlm.nih.gov/20215588/"",""year"":""2010"",""journal"":""The Plant cell"",""authors"":""Beck M, Komis G, Müller J, Menzel D, Samaj J."",""matched_aliases"":[""ANP2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"
