query	query_gene_id	query_protein_id	source_reference	hit_rank	swissprot_acc	swissprot_entry	database_section	target_gene_id	description	organism	homolog_gene_name	percent_identity	alignment_length	query_coverage	evalue	bitscore	confidence	evidence_type	source_db	reference_gene_id	reference_function_zh	reference_function_en	reference_papers_json
TkA03G290330	TkA03G290330	TkA03G290330.1	TK1151	2	Q93ZB2	KO1_ARATH	Swiss-Prot		sp|Q93ZB2|KO1_ARATH Ent-kaurene oxidase, chloroplastic	Arabidopsis thaliana	KO	58.6	493	95.499	2.76e-208	590.0	High	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	At5g25900	催化对映贝壳杉烯的 4-甲基基团的三个连续氧化，产生贝壳杉烯酸，这是赤霉素 生物合成的关键步骤。	Catalyzes three successive oxidations of the 4-methyl group of ent-kaurene giving kaurenoic acid, a key step in gibberellins (GAs) biosynthesis.	"[{""pmid"":""20698828"",""title"":""Characterization of the kaurene oxidase CYP701A3, a multifunctional cytochrome P450 from gibberellin biosynthesis."",""doi"":""10.1042/bj20100597"",""url"":""https://pubmed.ncbi.nlm.nih.gov/20698828/"",""year"":""2010"",""journal"":""The Biochemical journal"",""authors"":""Morrone D, Chen X, Coates RM, Peters RJ."",""matched_aliases"":[""CYP701A3""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"
TkA03G290330	TkA03G290330	TkA03G290330.1	TK1151	3	Q5Z5R4	C7016_ORYSJ	Swiss-Prot		sp|Q5Z5R4|C7016_ORYSJ Ent-kaurene oxidase 2	Oryza sativa subsp. japonica	CYP701A6	52.7	490	95.108	1.65e-181	521.0	High	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	Os06g0570100	催化对映贝壳杉烯的 4-甲基基团的三个连续氧化，产生贝壳杉烯酸，这是赤霉素 生物合成的关键步骤。	Catalyzes three successive oxidations of the 4-methyl group of ent-kaurene giving kaurenoic acid, a key step in gibberellins (GAs) biosynthesis.	"[{""pmid"":""22247270"",""title"":""CYP701A8: a rice ent-kaurene oxidase paralog diverted to more specialized diterpenoid metabolism."",""doi"":""10.1104/pp.111.187518"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22247270/"",""year"":""2012"",""journal"":""Plant physiology"",""authors"":""Wang Q, Hillwig ML, Wu Y, Peters RJ."",""matched_aliases"":[""CYP701A6""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""22487175"",""title"":""A conformationally restricted uniconazole analogue as a specific inhibitor of rice ent-kaurene oxidase, CYP701A6."",""doi"":""10.1016/j.bmcl.2012.03.028"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22487175/"",""year"":""2012"",""journal"":""Bioorganic & medicinal chemistry letters"",""authors"":""Todoroki Y, Naiki K, Muramatsu T, Ohnishi T, Ueno K, Mizutani M, Hirai N."",""matched_aliases"":[""CYP701A6""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"
TkA03G290330	TkA03G290330	TkA03G290330.1	TK1151	4	Q5Z5R7	C701S_ORYSJ	Swiss-Prot		sp|Q5Z5R7|C701S_ORYSJ Ent-kaurene oxidase-like 3	Oryza sativa subsp. japonica	CYP701A19	53.7	462	90.215	1.39e-177	511.0	High	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	Os06g0569900	可能羟基化二萜。	May hydroxylate diterpenes.	[]
TkA03G290330	TkA03G290330	TkA03G290330.1	TK1151	5	Q0DBF4	C7018_ORYSJ	Swiss-Prot		sp|Q0DBF4|C7018_ORYSJ Ent-sandaracopimaradiene 3-hydroxylase	Oryza sativa subsp. japonica	CYP701A8	50.9	464	90.215	1.47e-173	501.0	High	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	Os06g0569500	可能催化二萜类化合物的羟基化，参与植物抗毒素合成。	May catalyze diterpenoid hydroxylation in phytoalexin biosynthesis.	"[{""pmid"":""22247270"",""title"":""CYP701A8: a rice ent-kaurene oxidase paralog diverted to more specialized diterpenoid metabolism."",""doi"":""10.1104/pp.111.187518"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22247270/"",""year"":""2012"",""journal"":""Plant physiology"",""authors"":""Wang Q, Hillwig ML, Wu Y, Peters RJ."",""matched_aliases"":[""CYP701A8""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""23795884"",""title"":""Picking sides: distinct roles for CYP76M6 and CYP76M8 in rice oryzalexin biosynthesis."",""doi"":""10.1042/bj20130574"",""url"":""https://pubmed.ncbi.nlm.nih.gov/23795884/"",""year"":""2013"",""journal"":""The Biochemical journal"",""authors"":""Wu Y, Wang Q, Hillwig ML, Peters RJ."",""matched_aliases"":[""CYP701A8""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""25758958"",""title"":""Optimization of recombinant expression enables discovery of novel cytochrome P450 activity in rice diterpenoid biosynthesis."",""doi"":""10.1007/s00253-015-6496-2"",""url"":""https://pubmed.ncbi.nlm.nih.gov/25758958/"",""year"":""2015"",""journal"":""Applied microbiology and biotechnology"",""authors"":""Kitaoka N, Wu Y, Xu M, Peters RJ."",""matched_aliases"":[""CYP701A8""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"