query	query_gene_id	query_protein_id	source_reference	hit_rank	swissprot_acc	swissprot_entry	database_section	target_gene_id	description	organism	homolog_gene_name	percent_identity	alignment_length	query_coverage	evalue	bitscore	confidence	evidence_type	source_db	reference_gene_id	reference_function_zh	reference_function_en	reference_papers_json
TkA02G360800	TkA02G360800	TkA02G360800.1	TK1151	1	B9DFG5	CARK5_ARATH	Swiss-Prot		sp|B9DFG5|CARK5_ARATH Protein CYTOSOLIC ABA RECEPTOR KINASE 5	Arabidopsis thaliana	CARK5	53.7	54	31.214	1.56e-12	67.8	Low	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	At3g59350	类受体的胞质激酶 (RLCK)，通过磷酸化和激活 ABA 受体（如 PYL8/RCAR3、PYR1/RCAR11、PYL1/RCAR12、PYL3/RCAR13 和 PYL2/RCAR14）来触发脱水响应的脱落酸 (ABA) 信号传导，以支持其单体化并增强 ABA 结合亲和力；这些受体反过来抑制作为 ABA 反应负调控因子的 PP2C 蛋白磷酸酶。	Receptor-like cytoplasmic kinase (RLCK) that triggers abscisic acid (ABA) signaling in response to dehydration by phosphorylating and activating ABA receptors (e.g. PYL8/RCAR3, PYR1/RCAR11, PYL1/RCAR12, PYL3/RCAR13 and PYL2/RCAR14) to support their monomerization and enhance their ABA binding affinity; they in turn repress PP2C protein phosphatases acting as negative regulators of ABA responses.	[]
TkA02G360800	TkA02G360800	TkA02G360800.1	TK1151	2	Q9ZW72	CARK6_ARATH	Swiss-Prot		sp|Q9ZW72|CARK6_ARATH Protein CYTOSOLIC ABA RECEPTOR KINASE 6	Arabidopsis thaliana	CARK6	60.9	46	26.59	1.83e-11	64.7	Low	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	At2g43230	类受体胞质激酶（RLCK），通过磷酸化并激活ABA受体以支持其单体化并增强其ABA结合能力，从而触发脱水响应的脱落酸（ABA）信号；它们反过来抑制作为ABA反应负调控因子的PP2C蛋白磷酸酶。	Receptor-like cytoplasmic kinase (RLCK) that triggers abscisic acid (ABA) signaling in response to dehydration by phosphorylating and activating ABA receptors to support their monomerization and enhance their ABA binding affinity; they in turn repress PP2C protein phosphatases acting as negative regulators of ABA responses.	"[{""pmid"":""30967269"",""title"":""CARK6 is involved in abscisic acid to regulate stress responses in Arabidopsis thaliana."",""doi"":""10.1016/j.bbrc.2019.03.180"",""url"":""https://pubmed.ncbi.nlm.nih.gov/30967269/"",""year"":""2019"",""journal"":""Biochemical and biophysical research communications"",""authors"":""Wang J; Zhang Q; Yu Q; Peng L; Wang J; Dai Q; Yang Y; Li X"",""matched_aliases"":[""CARK6""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""39673241"",""title"":""Catalytically inactive subgroup VIII receptor-like cytoplasmic kinases regulate the immune-triggered oxidative burst in Arabidopsis thaliana."",""doi"":""10.1093/jxb/erae486"",""url"":""https://pubmed.ncbi.nlm.nih.gov/39673241/"",""year"":""2025"",""journal"":""Journal of experimental botany"",""authors"":""Gonçalves Dias M; Dharmasena T; Gonzalez-Ferrer C; Maika JE; Miguel VN; Dou R; Rodriguez Gallo MC; Bredow M; Siegel KR; Uhrig RG; Simon R; Monaghan J"",""matched_aliases"":[""CARK6""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false}]"
