query	query_gene_id	query_protein_id	source_reference	hit_rank	swissprot_acc	swissprot_entry	database_section	target_gene_id	description	organism	homolog_gene_name	percent_identity	alignment_length	query_coverage	evalue	bitscore	confidence	evidence_type	source_db	reference_gene_id	reference_function_zh	reference_function_en	reference_papers_json
TkA01G416050	TkA01G416050	TkA01G416050.1	TK1151	1	Q8VYT3	CIK3_ARATH	Swiss-Prot		sp|Q8VYT3|CIK3_ARATH Protein CLAVATA3 INSENSITIVE RECEPTOR KINASE 3	Arabidopsis thaliana	CIK3	72.2	640	98.587	1.14e-247	700.0	High	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	At4g30520	可能作为受体激酶，参与分生组织稳态及原韧皮部分化的调控。	May act as a receptor kinase regulating meristem homeostasis and protophloem differentiation.	"[{""pmid"":""29789310"",""title"":""CLERK is a novel receptor kinase required for sensing of root-active CLE peptides in  Arabidopsis ."",""doi"":""10.1242/dev.162354"",""url"":""https://pubmed.ncbi.nlm.nih.gov/29789310/"",""year"":""2018"",""journal"":""Development (Cambridge, England)"",""authors"":""Anne P, Amiguet-Vercher A, Brandt B, Kalmbach L, Geldner N, Hothorn M, Hardtke CS."",""matched_aliases"":[""SARK""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"
TkA01G416050	TkA01G416050	TkA01G416050.1	TK1151	2	Q0WVM4	CIK2_ARATH	Swiss-Prot		sp|Q0WVM4|CIK2_ARATH Protein CLAVATA3 INSENSITIVE RECEPTOR KINASE 2	Arabidopsis thaliana	CIK2	71.1	634	98.116	7.56e-240	680.0	High	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	At2g23950	可能作为受体激酶，参与分生组织稳态及原韧皮部分化的调控。	May act as a receptor kinase regulating meristem homeostasis and protophloem differentiation.	"[{""pmid"":""29789310"",""title"":""CLERK is a novel receptor kinase required for sensing of root-active CLE peptides in  Arabidopsis ."",""doi"":""10.1242/dev.162354"",""url"":""https://pubmed.ncbi.nlm.nih.gov/29789310/"",""year"":""2018"",""journal"":""Development (Cambridge, England)"",""authors"":""Anne P, Amiguet-Vercher A, Brandt B, Kalmbach L, Geldner N, Hothorn M, Hardtke CS."",""matched_aliases"":[""CLERK""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""34651321"",""title"":""A CLE-BAM-CIK signalling module controls root protophloem differentiation in Arabidopsis."",""doi"":""10.1111/nph.17791"",""url"":""https://pubmed.ncbi.nlm.nih.gov/34651321/"",""year"":""2022"",""journal"":""The New phytologist"",""authors"":""Hu C, Zhu Y, Cui Y, Zeng L, Li S, Meng F, Huang S, Wang W, Kui H, Yi J, Li J, Wan D, Gou X."",""matched_aliases"":[""CIK2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"
TkA01G416050	TkA01G416050	TkA01G416050.1	TK1151	3	Q9LFS4	CIK5_ARATH	Swiss-Prot		sp|Q9LFS4|CIK5_ARATH Protein CLAVATA3 INSENSITIVE RECEPTOR KINASE 5	Arabidopsis thaliana	CIK5	64.2	648	100.0	1.02e-210	606.0	High	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	At5g16000	可能作为受体激酶，参与分生组织稳态及原韧皮部分化的调控。	May act as a receptor kinase regulating meristem homeostasis and protophloem differentiation.	"[{""pmid"":""19112492"",""title"":""Regulated nuclear trafficking of rpL10A mediated by NIK1 represents a defense strategy of plant cells against virus."",""doi"":""10.1371/journal.ppat.1000247"",""url"":""https://pubmed.ncbi.nlm.nih.gov/19112492/"",""year"":""2008"",""journal"":""PLoS pathogens"",""authors"":""Carvalho CM, Santos AA, Pires SR, Rocha CS, Saraiva DI, Machado JP, Mattos EC, Fietto LG, Fontes EP."",""matched_aliases"":[""NIK1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""25707794"",""title"":""NIK1-mediated translation suppression functions as a plant antiviral immunity mechanism."",""doi"":""10.1038/nature14171"",""url"":""https://pubmed.ncbi.nlm.nih.gov/25707794/"",""year"":""2015"",""journal"":""Nature"",""authors"":""Zorzatto C, Machado JP, Lopes KV, Nascimento KJ, Pereira WA, Brustolini OJ, Reis PA, Calil IP, Deguchi M, Sachetto-Martins G, Gouveia BC, Loriato VA, Silva MA, Silva FF, Santos AA, Chory J, Fontes EP."",""matched_aliases"":[""NIK1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""29789310"",""title"":""CLERK is a novel receptor kinase required for sensing of root-active CLE peptides in  Arabidopsis ."",""doi"":""10.1242/dev.162354"",""url"":""https://pubmed.ncbi.nlm.nih.gov/29789310/"",""year"":""2018"",""journal"":""Development (Cambridge, England)"",""authors"":""Anne P, Amiguet-Vercher A, Brandt B, Kalmbach L, Geldner N, Hothorn M, Hardtke CS."",""matched_aliases"":[""NIK1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"
TkA01G416050	TkA01G416050	TkA01G416050.1	TK1151	5	Q8RY65	CIK6_ARATH	Swiss-Prot		sp|Q8RY65|CIK6_ARATH Protein CLAVATA3 INSENSITIVE RECEPTOR KINASE 6	Arabidopsis thaliana	CIK6	65.1	630	97.959	1.66e-203	587.0	High	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	At3g25560	受体激酶，与其他CIK（如CIK1、CIK2、CIK3、CIK5和CIK6）冗余作用，作为CLV1、CLV2/CRN和RPK2的共受体，并且需要通过磷酸化介导CLAVATA家族肽（如CLV3、CLE25、CLE26和CLE45）信号；该信号调控原韧皮部分化及维持茎尖分生组织（SAM）和根尖分生组织（RAM）的稳态，并作用于BRX和OPS下游。	Receptor kinase acting, redundantly with other CIKs (e.g. CIK1, CIK2, CIK3, CIK5 and CIK6), as a coreceptor of CLV1, CLV2/CRN and RPK2, and required for CLAVATA-family peptides (e.g. CLV3, CLE25, CLE26 and CLE45) signaling through phosphorylation; this signaling regulates protophloem differentiation and the maintenance of shoot apical meristem (SAM) and root apical meristem (RAM) homeostasis, and acts down-stream of BRX and OPS.	[]
TkA01G416050	TkA01G416050	TkA01G416050.1	TK1151	4	Q9FP13	SERL2_ORYSJ	Swiss-Prot		sp|Q9FP13|SERL2_ORYSJ LRR receptor kinase SERL2	Oryza sativa subsp. japonica	SERL2	69.3	567	87.912	2.19e-210	605.0	High	TK1151 direct protein BLASTP	UniProt Swiss-Prot local database (DIAMOND)	Os06g0274500	可能参与防御反应的 LRR 受体激酶。	LRR receptor kinase that may be involved in defense response.	[]