query	query_gene_id	query_protein_id	source_reference	hit_rank	swissprot_acc	swissprot_entry	database_section	target_gene_id	description	organism	homolog_gene_name	percent_identity	alignment_length	query_coverage	evalue	bitscore	confidence	evidence_type	source_db	reference_gene_id	reference_function_zh	reference_function_en	reference_papers_json
LXL04_032765	gene-LXL04_032765	KAL4560612.1	OH-1004	1	Q8LGJ5	PCO2_ARATH	Swiss-Prot		Plant cysteine oxidase 2 OS=Arabidopsis thaliana OX=3702 GN=PCO2 PE=1 SV=1	Arabidopsis thaliana	PCO2	46.781	233	82.707	1.89e-63	203.0	moderate_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At5g39890	催化 N 端半胱氨酸残基（N-Cys）的氧化，从而为蛋白参与 N 端法则途径介导的蛋白酶体降解做准备，此过程在 N-端法则酶 ATE1、ATE2 和 PRT6 的作用之前。	Catalyzes the oxidation of N-terminal cysteine residues (N-Cys), thus preparing the protein for N-end rule pathway-mediated proteasomal degradation, upstream of the N-end rule enzymes ATE1, ATE2 and PRT6.	"[{""pmid"":""33207269"",""title"":""Molecular basis for cysteine oxidation by plant cysteine oxidases from Arabidopsis thaliana."",""doi"":""10.1016/j.jsb.2020.107663"",""url"":""https://pubmed.ncbi.nlm.nih.gov/33207269/"",""year"":""2021"",""journal"":""Journal of structural biology"",""authors"":""Chen Z; Guo Q; Wu G; Wen J; Liao S; Xu C"",""matched_aliases"":[""AtPCO2"",""PCO2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false}]"
LXL04_032765	gene-LXL04_032765	KAL4560612.1	OH-1004	2	Q9LXG9	PCO1_ARATH	Swiss-Prot		Plant cysteine oxidase 1 OS=Arabidopsis thaliana OX=3702 GN=PCO1 PE=1 SV=1	Arabidopsis thaliana	PCO1	42.629	251	87.594	1.57e-61	198.0	moderate_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At5g15120	催化 N 端半胱氨酸残基（N-Cys）的氧化，从而为蛋白参与 N 端法则途径介导的蛋白酶体降解做准备，此过程在 N-端法则酶 ATE1、ATE2 和 PRT6 的作用之前。	Catalyzes the oxidation of N-terminal cysteine residues (N-Cys), thus preparing the protein for N-end rule pathway-mediated proteasomal degradation, upstream of the N-end rule enzymes ATE1, ATE2 and PRT6.	[]
LXL04_032765	gene-LXL04_032765	KAL4560612.1	OH-1004	3	Q1G3U6	PCO3_ARATH	Swiss-Prot		Plant cysteine oxidase 3 OS=Arabidopsis thaliana OX=3702 GN=PCO3 PE=1 SV=1	Arabidopsis thaliana	PCO3	33.813	278	93.233	1.37e-46	160.0	moderate_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At1g18490	催化N端半胱氨酸残基（N-Cys）的氧化，从而为N端规则途径介导的蛋白酶体降解做准备，位于N端规则酶ATE1、ATE2和PRT6（可能）的上游。	Catalyzes the oxidation of N-terminal cysteine residues (N-Cys), thus preparing the protein for N-end rule pathway-mediated proteasomal degradation, upstream of the N-end rule enzymes ATE1, ATE2 and PRT6 (Probable).	[]
LXL04_032765	gene-LXL04_032765	KAL4560612.1	OH-1004	4	Q9SJI9	PCO4_ARATH	Swiss-Prot		Plant cysteine oxidase 4 OS=Arabidopsis thaliana OX=3702 GN=PCO4 PE=1 SV=2	Arabidopsis thaliana	PCO4	37.021	235	81.203	5.55e-44	152.0	moderate_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At2g42670	催化N端半胱氨酸残基（N-Cys）的氧化，从而为N端规则途径介导的蛋白酶体降解做准备，位于N端规则酶ATE1、ATE2和PRT6（可能）的上游。	Catalyzes the oxidation of N-terminal cysteine residues (N-Cys), thus preparing the protein for N-end rule pathway-mediated proteasomal degradation, upstream of the N-end rule enzymes ATE1, ATE2 and PRT6 (Probable).	"[{""pmid"":""29848548"",""title"":""The plant cysteine oxidases from Arabidopsis thaliana are kinetically tailored to act as oxygen sensors."",""doi"":""10.1074/jbc.ra118.003496"",""url"":""https://pubmed.ncbi.nlm.nih.gov/29848548/"",""year"":""2018"",""journal"":""The Journal of biological chemistry"",""authors"":""White MD; Kamps JJAG; East S; Taylor Kearney LJ; Flashman E"",""matched_aliases"":[""AtPCO4""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""32868422"",""title"":""Structures of Arabidopsis thaliana oxygen-sensing plant cysteine oxidases 4 and 5 enable targeted manipulation of their activity."",""doi"":""10.1073/pnas.2000206117"",""url"":""https://pubmed.ncbi.nlm.nih.gov/32868422/"",""year"":""2020"",""journal"":""Proceedings of the National Academy of Sciences of the United States of America"",""authors"":""White MD; Dalle Carbonare L; Lavilla Puerta M; Iacopino S; Edwards M; Dunne K; Pires E; Levy C; McDonough MA; Licausi F; Flashman E"",""matched_aliases"":[""PCO4""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""33207269"",""title"":""Molecular basis for cysteine oxidation by plant cysteine oxidases from Arabidopsis thaliana."",""doi"":""10.1016/j.jsb.2020.107663"",""url"":""https://pubmed.ncbi.nlm.nih.gov/33207269/"",""year"":""2021"",""journal"":""Journal of structural biology"",""authors"":""Chen Z; Guo Q; Wu G; Wen J; Liao S; Xu C"",""matched_aliases"":[""PCO4""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false}]"
LXL04_032765	gene-LXL04_032765	KAL4560612.1	OH-1004	5	Q9LXT4	PCO5_ARATH	Swiss-Prot		Plant cysteine oxidase 5 OS=Arabidopsis thaliana OX=3702 GN=PCO5 PE=1 SV=1	Arabidopsis thaliana	PCO5	36.709	237	81.579	2.5e-42	147.0	moderate_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At3g58670	催化N端半胱氨酸残基（N-Cys）的氧化，从而为N端规则途径介导的蛋白酶体降解做准备，位于N端规则酶ATE1、ATE2和PRT6（可能）的上游。	Catalyzes the oxidation of N-terminal cysteine residues (N-Cys), thus preparing the protein for N-end rule pathway-mediated proteasomal degradation, upstream of the N-end rule enzymes ATE1, ATE2 and PRT6 (Probable).	"[{""pmid"":""32868422"",""title"":""Structures of Arabidopsis thaliana oxygen-sensing plant cysteine oxidases 4 and 5 enable targeted manipulation of their activity."",""doi"":""10.1073/pnas.2000206117"",""url"":""https://pubmed.ncbi.nlm.nih.gov/32868422/"",""year"":""2020"",""journal"":""Proceedings of the National Academy of Sciences of the United States of America"",""authors"":""White MD; Dalle Carbonare L; Lavilla Puerta M; Iacopino S; Edwards M; Dunne K; Pires E; Levy C; McDonough MA; Licausi F; Flashman E"",""matched_aliases"":[""PCO5""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""33207269"",""title"":""Molecular basis for cysteine oxidation by plant cysteine oxidases from Arabidopsis thaliana."",""doi"":""10.1016/j.jsb.2020.107663"",""url"":""https://pubmed.ncbi.nlm.nih.gov/33207269/"",""year"":""2021"",""journal"":""Journal of structural biology"",""authors"":""Chen Z; Guo Q; Wu G; Wen J; Liao S; Xu C"",""matched_aliases"":[""AtPCO5"",""PCO5""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false}]"