query	query_gene_id	query_protein_id	source_reference	hit_rank	swissprot_acc	swissprot_entry	database_section	target_gene_id	description	organism	homolog_gene_name	percent_identity	alignment_length	query_coverage	evalue	bitscore	confidence	evidence_type	source_db	reference_gene_id	reference_function_zh	reference_function_en	reference_papers_json
LXL04_030649	gene-LXL04_030649	KAL4566533.1	OH-1004	1	Q43867	PME1_ARATH	Swiss-Prot		Pectinesterase 1 OS=Arabidopsis thaliana OX=3702 GN=PME1 PE=1 SV=1	Arabidopsis thaliana	PME1	34.51	255	99.197	2.77e-38	143.0	moderate_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At1g53840	通过去甲基化果胶作用参与细胞壁的修饰（通过相似性推测）。	Acts in the modification of cell walls via demethylesterification of cell wall pectin (By similarity).	"[{""pmid"":""28741704"",""title"":""Methylation of protein phosphatase 2A-Influence of regulators and environmental stress factors."",""doi"":""10.1111/pce.13038"",""url"":""https://pubmed.ncbi.nlm.nih.gov/28741704/"",""year"":""2017"",""journal"":""Plant, cell & environment"",""authors"":""Creighton MT; Kolton A; Kataya ARA; Maple-Grødem J; Averkina IO; Heidari B; Lillo C"",""matched_aliases"":[""PME1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false}]"
LXL04_030649	gene-LXL04_030649	KAL4566533.1	OH-1004	2	Q9LUL8	PME26_ARATH	Swiss-Prot		Putative pectinesterase/pectinesterase inhibitor 26 OS=Arabidopsis thaliana OX=3702 GN=PME26 PE=2 SV=1	Arabidopsis thaliana	PME26	36.364	253	99.197	3.73e-37	142.0	moderate_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At3g14300	通过细胞壁果胶的去甲基酯化作用来修饰细胞壁。	Acts in the modification of cell walls via demethylesterification of cell wall pectin.	[]
LXL04_030649	gene-LXL04_030649	KAL4566533.1	OH-1004	7	Q9SG77	PME24_ARATH	Swiss-Prot		Putative pectinesterase/pectinesterase inhibitor 24 OS=Arabidopsis thaliana OX=3702 GN=PME24 PE=3 SV=1	Arabidopsis thaliana	PME24	27.426	237	95.181	1.09e-16	82.4	weak_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At3g10710	通过细胞壁果胶的去甲基酯化作用来修饰细胞壁。	Acts in the modification of cell walls via demethylesterification of cell wall pectin.	[]
LXL04_030649	gene-LXL04_030649	KAL4566533.1	OH-1004	6	Q9SB38	PMEI4_ARATH	Swiss-Prot		Pectinesterase inhibitor 4 OS=Arabidopsis thaliana OX=3702 GN=PMEI4 PE=1 SV=1	Arabidopsis thaliana	PMEI4	33.333	165	63.052	1.02e-17	81.6	moderate_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At4g25250	果胶甲基酯酶（PME）抑制剂，可靶向根系表达的PME17和PME3，其作用依赖于pH值，主要在略酸性条件下（pH 6.3和5.0）起作用，但在pH 7.5时不发生作用；该过程依赖于参与分子间和分子内相互作用的氨基酸质子化状态的变化。	Pectin methylesterase (PME) inhibitor that can target the root-expressed PME17 and PME3 in a pH-dependent manner, mainly in slightly acidic conditions (pH 6.3 and 5.0) but not at pH 7.5; this processus relies on changes in the protonation of amino acids involved in intermolecular and intramolecular interactions.	"[{""pmid"":""25826258"",""title"":""Arabidopsis PME17 Activity can be Controlled by Pectin Methylesterase Inhibitor4."",""doi"":""10.4161/15592324.2014.983351"",""url"":""https://pubmed.ncbi.nlm.nih.gov/25826258/"",""year"":""2015"",""journal"":""Plant signaling & behavior"",""authors"":""Sénéchal F; Mareck A; Marcelo P; Lerouge P; Pelloux J"",""matched_aliases"":[""PMEI4""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""28034952"",""title"":""Combined Experimental and Computational Approaches Reveal Distinct pH Dependence of Pectin Methylesterase Inhibitors."",""doi"":""10.1104/pp.16.01790"",""url"":""https://pubmed.ncbi.nlm.nih.gov/28034952/"",""year"":""2017"",""journal"":""Plant physiology"",""authors"":""Hocq L, Sénéchal F, Lefebvre V, Lehner A, Domon JM, Mollet JC, Dehors J, Pageau K, Marcelo P, Guérineau F, Kolšek K, Mercadante D, Pelloux J."",""matched_aliases"":[""AtPMEI4""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"