query	query_gene_id	query_protein_id	source_reference	hit_rank	swissprot_acc	swissprot_entry	database_section	target_gene_id	description	organism	homolog_gene_name	percent_identity	alignment_length	query_coverage	evalue	bitscore	confidence	evidence_type	source_db	reference_gene_id	reference_function_zh	reference_function_en	reference_papers_json
LXL04_028444	gene-LXL04_028444	KAL4564382.1	OH-1004	1	Q9SZW4	HMA2_ARATH	Swiss-Prot		Cadmium/zinc-transporting ATPase HMA2 OS=Arabidopsis thaliana OX=3702 GN=HMA2 PE=2 SV=1	Arabidopsis thaliana	HMA2	55.067	977	99.578	0.0	1015.0	strong_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At4g30110	在锌的运输和稳态中起重要作用。	Plays an important role in zinc transport and homeostasis.	"[{""pmid"":""15100400"",""title"":""P-type ATPase heavy metal transporters with roles in essential zinc homeostasis in Arabidopsis."",""doi"":""10.1105/tpc.020487"",""url"":""https://pubmed.ncbi.nlm.nih.gov/15100400/"",""year"":""2004"",""journal"":""The Plant cell"",""authors"":""Hussain D; Haydon MJ; Wang Y; Wong E; Sherson SM; Young J; Camakaris J; Harper JF; Cobbett CS"",""matched_aliases"":[""HMA2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false}]"
LXL04_028444	gene-LXL04_028444	KAL4564382.1	OH-1004	2	O64474	HMA4_ARATH	Swiss-Prot		Putative cadmium/zinc-transporting ATPase HMA4 OS=Arabidopsis thaliana OX=3702 GN=HMA4 PE=1 SV=2	Arabidopsis thaliana	HMA4	60.826	799	80.591	0.0	971.0	strong_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At2g19110	参与镉/锌的运输。	Involved in cadmium/zinc transport.	[]
LXL04_028444	gene-LXL04_028444	KAL4564382.1	OH-1004	3	P0CW78	HMA3B_ARATH	Swiss-Prot		Cadmium/zinc-transporting ATPase HMA3 OS=Arabidopsis thaliana OX=3702 GN=HMA3 PE=1 SV=1	Arabidopsis thaliana	HMA3	62.034	698	73.101	0.0	906.0	strong_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10		在异源系统中，参与镉和铅的转运，但不参与锌的转运。	In a heterologous system, involved in cadmium and lead transport, but not in zinc transport.	[]
LXL04_028444	gene-LXL04_028444	KAL4564382.1	OH-1004	4	A3BF39	HMA2_ORYSJ	Swiss-Prot		Cadmium/zinc-transporting ATPase HMA2 OS=Oryza sativa subsp. japonica OX=39947 GN=HMA2 PE=1 SV=1	Oryza sativa subsp. japonica	HMA2	61.623	727	75.316	0.0	898.0	strong_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	Os06g0700700	锌/镉转运蛋白，在促进锌和镉从根向茎的转运中起关键作用。	Zinc/cadmium transporter that plays an essential role in promoting translocation of zinc and cadmium from roots to shoots.	"[{""pmid"":""21388416"",""title"":""Cadmium retention in rice roots is influenced by cadmium availability, chelation and translocation."",""doi"":""10.1111/j.1365-3040.2011.02299.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/21388416/"",""year"":""2011"",""journal"":""Plant, cell & environment"",""authors"":""Nocito FF; Lancilli C; Dendena B; Lucchini G; Sacchi GA"",""matched_aliases"":[""OsHMA2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""22123790"",""title"":""Mutations in rice (Oryza sativa) heavy metal ATPase 2 (OsHMA2) restrict the translocation of zinc and cadmium."",""doi"":""10.1093/pcp/pcr166"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22123790/"",""year"":""2012"",""journal"":""Plant & cell physiology"",""authors"":""Satoh-Nagasawa N; Mori M; Nakazawa N; Kawamoto T; Nagato Y; Sakurai K; Takahashi H; Watanabe A; Akagi H"",""matched_aliases"":[""OsHMA2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""22548273"",""title"":""The OsHMA2 transporter is involved in root-to-shoot translocation of Zn and Cd in rice."",""doi"":""10.1111/j.1365-3040.2012.02527.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22548273/"",""year"":""2012"",""journal"":""Plant, cell & environment"",""authors"":""Takahashi R; Ishimaru Y; Shimo H; Ogo Y; Senoura T; Nishizawa NK; Nakanishi H"",""matched_aliases"":[""OsHMA2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""23575418"",""title"":""Preferential delivery of zinc to developing tissues in rice is mediated by P-type heavy metal ATPase OsHMA2."",""doi"":""10.1104/pp.113.216564"",""url"":""https://pubmed.ncbi.nlm.nih.gov/23575418/"",""year"":""2013"",""journal"":""Plant physiology"",""authors"":""Yamaji N; Xia J; Mitani-Ueno N; Yokosho K; Feng Ma J"",""matched_aliases"":[""OsHMA2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false}]"
LXL04_028444	gene-LXL04_028444	KAL4564382.1	OH-1004	5	Q8H384	HMA3_ORYSJ	Swiss-Prot		Cadmium/zinc-transporting ATPase HMA3 OS=Oryza sativa subsp. japonica OX=39947 GN=HMA3 PE=1 SV=1	Oryza sativa subsp. japonica	HMA3	56.377	690	72.257	0.0	697.0	strong_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	Os07g0232900	根特异性镉 (Cd) 转运蛋白，可介导根液泡中的 Cd 外排。	Root-specific cadmium (Cd) transporter that mediates Cd efflux in root vacuoles.	"[{""pmid"":""20823253"",""title"":""Gene limiting cadmium accumulation in rice."",""doi"":""10.1073/pnas.1005396107"",""url"":""https://pubmed.ncbi.nlm.nih.gov/20823253/"",""year"":""2010"",""journal"":""Proceedings of the National Academy of Sciences of the United States of America"",""authors"":""Ueno D; Yamaji N; Kono I; Huang CF; Ando T; Yano M; Ma JF"",""matched_aliases"":[""OsHMA3""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""20840506"",""title"":""OsHMA3, a P1B-type of ATPase affects root-to-shoot cadmium translocation in rice by mediating efflux into vacuoles."",""doi"":""10.1111/j.1469-8137.2010.03459.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/20840506/"",""year"":""2011"",""journal"":""The New phytologist"",""authors"":""Miyadate H; Adachi S; Hiraizumi A; Tezuka K; Nakazawa N; Kawamoto T; Katou K; Kodama I; Sakurai K; Takahashi H; Satoh-Nagasawa N; Watanabe A; Fujimura T; Akagi H"",""matched_aliases"":[""OsHMA3""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""25151617"",""title"":""Overexpression of OsHMA3 enhances Cd tolerance and expression of Zn transporter genes in rice."",""doi"":""10.1093/jxb/eru340"",""url"":""https://pubmed.ncbi.nlm.nih.gov/25151617/"",""year"":""2014"",""journal"":""Journal of experimental botany"",""authors"":""Sasaki A; Yamaji N; Ma JF"",""matched_aliases"":[""OsHMA3""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false}]"
