query	query_gene_id	query_protein_id	source_reference	hit_rank	swissprot_acc	swissprot_entry	database_section	target_gene_id	description	organism	homolog_gene_name	percent_identity	alignment_length	query_coverage	evalue	bitscore	confidence	evidence_type	source_db	reference_gene_id	reference_function_zh	reference_function_en	reference_papers_json
LXL04_027372	gene-LXL04_027372	KAL4563331.1	OH-1004	1	C0LGU5	CIK4_ARATH	Swiss-Prot		Protein CLAVATA3 INSENSITIVE RECEPTOR KINASE 4 OS=Arabidopsis thaliana OX=3702 GN=CIK4 PE=1 SV=1	Arabidopsis thaliana	CIK4	53.614	332	94.774	1.27e-104	320.0	strong_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At5g45780	受体激酶，与其他CIK（如CIK1、CIK2、CIK3、CIK5和CIK6）冗余作用，作为CLV1、CLV2/CRN和RPK2的共受体，并且需要通过磷酸化介导CLAVATA家族肽（如CLV3、CLE25、CLE26和CLE45）信号；该信号调控原韧皮部分化及维持茎尖分生组织（SAM）和根尖分生组织（RAM）的稳态，并作用于BRX和OPS下游。	Receptor kinase acting, redundantly with other CIKs (e.g. CIK1, CIK2, CIK3, CIK5 and CIK6), as a coreceptor of CLV1, CLV2/CRN and RPK2, and required for CLAVATA-family peptides (e.g. CLV3, CLE25, CLE26 and CLE45) signaling through phosphorylation; this signaling regulates protophloem differentiation and the maintenance of shoot apical meristem (SAM) and root apical meristem (RAM) homeostasis, and acts down-stream of BRX and OPS.	[]
LXL04_027372	gene-LXL04_027372	KAL4563331.1	OH-1004	2	Q93ZS4	CIK1_ARATH	Swiss-Prot		Protein CLAVATA3 INSENSITIVE RECEPTOR KINASE 1 OS=Arabidopsis thaliana OX=3702 GN=CIK1 PE=1 SV=1	Arabidopsis thaliana	CIK1	78.107	169	58.537	1.39e-82	263.0	moderate_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At1g60800	受体激酶，与其他CIK（如CIK1、CIK2、CIK3、CIK5和CIK6）冗余作用，作为CLV1、CLV2/CRN和RPK2的共受体，并需要通过磷酸化介导CLAVATA家族肽（如CLV3）信号；该信号调控原韧皮部分化以及维持芽顶分生组织（SAM）和根顶分生组织（RAM）稳态，并在BRX和OPS下游发挥作用。	Receptor kinase acting, redundantly with other CIKs (e.g. CIK1, CIK2, CIK3, CIK5 and CIK6), as a coreceptor of CLV1, CLV2/CRN and RPK2, and required for CLAVATA-family peptides (e.g. CLV3) signaling through phosphorylation; this signaling regulates protophloem differentiation and the maintenance of shoot apical meristem (SAM) and root apical meristem (RAM) homeostasis, and acts down-stream of BRX and OPS.	[]
LXL04_027372	gene-LXL04_027372	KAL4563331.1	OH-1004	3	Q9SKG5	SERK4_ARATH	Swiss-Prot		Somatic embryogenesis receptor kinase 4 OS=Arabidopsis thaliana OX=3702 GN=SERK4 PE=1 SV=2	Arabidopsis thaliana	SERK4	50.709	282	78.049	4.57e-78	251.0	strong_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At2g13790	双特异性激酶作用于含丝氨酸/苏氨酸和含酪氨酸的底物。	Dual specificity kinase acting on both serine/threonine- and tyrosine-containing substrates.	"[{""pmid"":""17600708"",""title"":""BAK1 and BKK1 regulate brassinosteroid-dependent growth and brassinosteroid-independent cell-death pathways."",""doi"":""10.1016/j.cub.2007.05.036"",""url"":""https://pubmed.ncbi.nlm.nih.gov/17600708/"",""year"":""2007"",""journal"":""Current biology : CB"",""authors"":""He K; Gou X; Yuan T; Lin H; Asami T; Yoshida S; Russell SD; Li J"",""matched_aliases"":[""BKK1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""18667726"",""title"":""Arabidopsis SOMATIC EMBRYOGENESIS RECEPTOR KINASE proteins serve brassinosteroid-dependent and -independent signaling pathways."",""doi"":""10.1104/pp.108.123216"",""url"":""https://pubmed.ncbi.nlm.nih.gov/18667726/"",""year"":""2008"",""journal"":""Plant physiology"",""authors"":""Albrecht C; Russinova E; Kemmerling B; Kwaaitaal M; de Vries SC"",""matched_aliases"":[""SERK4""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""34535661"",""title"":""The Arabidopsis MIK2 receptor elicits immunity by sensing a conserved signature from phytocytokines and microbes."",""doi"":""10.1038/s41467-021-25580-w"",""url"":""https://pubmed.ncbi.nlm.nih.gov/34535661/"",""year"":""2021"",""journal"":""Nature communications"",""authors"":""Hou S; Liu D; Huang S; Luo D; Liu Z; Xiang Q; Wang P; Mu R; Han Z; Chen S; Chai J; Shan L; He P"",""matched_aliases"":[""SERK4""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false}]"
LXL04_027372	gene-LXL04_027372	KAL4563331.1	OH-1004	4	Q8RY65	CIK6_ARATH	Swiss-Prot		Protein CLAVATA3 INSENSITIVE RECEPTOR KINASE 6 OS=Arabidopsis thaliana OX=3702 GN=CIK6 PE=1 SV=1	Arabidopsis thaliana	CIK6	75.148	169	58.537	1.24e-77	250.0	moderate_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At3g25560	受体激酶，与其他CIK（如CIK1、CIK2、CIK3、CIK5和CIK6）冗余作用，作为CLV1、CLV2/CRN和RPK2的共受体，并且需要通过磷酸化介导CLAVATA家族肽（如CLV3、CLE25、CLE26和CLE45）信号；该信号调控原韧皮部分化及维持茎尖分生组织（SAM）和根尖分生组织（RAM）的稳态，并作用于BRX和OPS下游。	Receptor kinase acting, redundantly with other CIKs (e.g. CIK1, CIK2, CIK3, CIK5 and CIK6), as a coreceptor of CLV1, CLV2/CRN and RPK2, and required for CLAVATA-family peptides (e.g. CLV3, CLE25, CLE26 and CLE45) signaling through phosphorylation; this signaling regulates protophloem differentiation and the maintenance of shoot apical meristem (SAM) and root apical meristem (RAM) homeostasis, and acts down-stream of BRX and OPS.	[]
LXL04_027372	gene-LXL04_027372	KAL4563331.1	OH-1004	6	Q9LFS4	CIK5_ARATH	Swiss-Prot		Protein CLAVATA3 INSENSITIVE RECEPTOR KINASE 5 OS=Arabidopsis thaliana OX=3702 GN=CIK5 PE=1 SV=1	Arabidopsis thaliana	CIK5	74.118	170	58.885	3.91e-77	249.0	moderate_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At5g16000	可能作为受体激酶，参与分生组织稳态及原韧皮部分化的调控。	May act as a receptor kinase regulating meristem homeostasis and protophloem differentiation.	"[{""pmid"":""19112492"",""title"":""Regulated nuclear trafficking of rpL10A mediated by NIK1 represents a defense strategy of plant cells against virus."",""doi"":""10.1371/journal.ppat.1000247"",""url"":""https://pubmed.ncbi.nlm.nih.gov/19112492/"",""year"":""2008"",""journal"":""PLoS pathogens"",""authors"":""Carvalho CM, Santos AA, Pires SR, Rocha CS, Saraiva DI, Machado JP, Mattos EC, Fietto LG, Fontes EP."",""matched_aliases"":[""NIK1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""25707794"",""title"":""NIK1-mediated translation suppression functions as a plant antiviral immunity mechanism."",""doi"":""10.1038/nature14171"",""url"":""https://pubmed.ncbi.nlm.nih.gov/25707794/"",""year"":""2015"",""journal"":""Nature"",""authors"":""Zorzatto C, Machado JP, Lopes KV, Nascimento KJ, Pereira WA, Brustolini OJ, Reis PA, Calil IP, Deguchi M, Sachetto-Martins G, Gouveia BC, Loriato VA, Silva MA, Silva FF, Santos AA, Chory J, Fontes EP."",""matched_aliases"":[""NIK1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""29789310"",""title"":""CLERK is a novel receptor kinase required for sensing of root-active CLE peptides in  Arabidopsis ."",""doi"":""10.1242/dev.162354"",""url"":""https://pubmed.ncbi.nlm.nih.gov/29789310/"",""year"":""2018"",""journal"":""Development (Cambridge, England)"",""authors"":""Anne P, Amiguet-Vercher A, Brandt B, Kalmbach L, Geldner N, Hothorn M, Hardtke CS."",""matched_aliases"":[""NIK1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"