query	query_gene_id	query_protein_id	source_reference	hit_rank	swissprot_acc	swissprot_entry	database_section	target_gene_id	description	organism	homolog_gene_name	percent_identity	alignment_length	query_coverage	evalue	bitscore	confidence	evidence_type	source_db	reference_gene_id	reference_function_zh	reference_function_en	reference_papers_json
LXL04_026847	gene-LXL04_026847	KAL4562816.1	OH-1004	1	Q9SI72	PMEI9_ARATH	Swiss-Prot		Pectinesterase inhibitor 9 OS=Arabidopsis thaliana OX=3702 GN=PMEI9 PE=1 SV=1	Arabidopsis thaliana	PMEI9	36.257	171	76.018	1.79e-26	104.0	moderate_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At1g62770	果胶甲酯酶 抑制剂，可能以中等 pH 依赖性方式靶向根部表达的 PME 和 PME3，主要在微酸性条件下，在某种程度上在 pH 7.5 下。	Pectin methylesterase (PME) inhibitor that probably targets root-expressed PME and PME3 in a moderate pH-dependent manner, mainly in slightly acidic conditions (pH 6.3 and 5.0) and to some extent at pH 7.5.	"[{""pmid"":""28034952"",""title"":""Combined Experimental and Computational Approaches Reveal Distinct pH Dependence of Pectin Methylesterase Inhibitors."",""doi"":""10.1104/pp.16.01790"",""url"":""https://pubmed.ncbi.nlm.nih.gov/28034952/"",""year"":""2017"",""journal"":""Plant physiology"",""authors"":""Hocq L, Sénéchal F, Lefebvre V, Lehner A, Domon JM, Mollet JC, Dehors J, Pageau K, Marcelo P, Guérineau F, Kolšek K, Mercadante D, Pelloux J."",""matched_aliases"":[""AtPMEI9""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"
LXL04_026847	gene-LXL04_026847	KAL4562816.1	OH-1004	2	Q9SB37	PMEI7_ARATH	Swiss-Prot		Pectinesterase inhibitor 7 OS=Arabidopsis thaliana OX=3702 GN=PMEI7 PE=1 SV=1	Arabidopsis thaliana	PMEI7	32.716	162	71.041	1.38e-21	91.3	moderate_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At4g25260	果胶甲酯酶 抑制剂，可以以 pH 依赖性方式靶向 PME3，主要在弱酸性条件下但不在 pH 7.0 下。	Pectin methylesterase (PME) inhibitor that can target PME3 in a pH-dependent manner, mainly in slightly acidic conditions (pH 6.0 and 5.0) but not at pH 7.0.	"[{""pmid"":""26183897"",""title"":""Tuning of Pectin Methylesterification: PECTIN METHYLESTERASE INHIBITOR 7 MODULATES THE PROCESSIVE ACTIVITY OF CO-EXPRESSED PECTIN METHYLESTERASE 3 IN A pH-DEPENDENT MANNER."",""doi"":""10.1074/jbc.m115.639534"",""url"":""https://pubmed.ncbi.nlm.nih.gov/26183897/"",""year"":""2015"",""journal"":""The Journal of biological chemistry"",""authors"":""Sénéchal F, L'Enfant M, Domon JM, Rosiau E, Crépeau MJ, Surcouf O, Esquivel-Rodriguez J, Marcelo P, Mareck A, Guérineau F, Kim HR, Mravec J, Bonnin E, Jamet E, Kihara D, Lerouge P, Ralet MC, Pelloux J, Rayon C."",""matched_aliases"":[""AtPMEI7""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""29109147"",""title"":""Structural and dynamical characterization of the pH-dependence of the pectin methylesterase-pectin methylesterase inhibitor complex."",""doi"":""10.1074/jbc.ra117.000197"",""url"":""https://pubmed.ncbi.nlm.nih.gov/29109147/"",""year"":""2017"",""journal"":""The Journal of biological chemistry"",""authors"":""Sénéchal F, Habrylo O, Hocq L, Domon JM, Marcelo P, Lefebvre V, Pelloux J, Mercadante D."",""matched_aliases"":[""PMEI7""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"
LXL04_026847	gene-LXL04_026847	KAL4562816.1	OH-1004	4	Q9STY5	PMI11_ARATH	Swiss-Prot		Pectinesterase inhibitor 11 OS=Arabidopsis thaliana OX=3702 GN=PMEI11 PE=2 SV=1	Arabidopsis thaliana	PMEI11	32.278	158	71.041	3.35e-20	87.8	moderate_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At3g47380	果胶甲酯酶（PME）抑制剂，参与对坏死性病原体反应中的细胞壁完整性维持。	Pectin methylesterase (PME) inhibitor involved in the maintenance of cell wall integrity in response to necrotrophic pathogens.	[]
LXL04_026847	gene-LXL04_026847	KAL4562816.1	OH-1004	5	Q84WE4	PMEI3_ARATH	Swiss-Prot		Pectinesterase inhibitor 3 OS=Arabidopsis thaliana OX=3702 GN=PMEI3 PE=2 SV=1	Arabidopsis thaliana	PMEI3	27.638	199	81.448	4.06e-14	71.6	weak_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At5g20740	果胶甲酯酶（PME）抑制因子，以pH依赖的方式作用于PME2、PME3等酶；主要在弱酸性条件（pH 6.3和5.0）下发挥作用，在pH 7.5时不发挥该作用。	Pectin methylesterase (PME) inhibitor that can target PMEs (e.g. PME2 and PME3) in a pH-dependent manner, mainly in slightly acidic conditions (pH 6.3 and 5.0) but not at pH 7.5.	"[{""pmid"":""36147700"",""title"":""Biochemical characterization of Pectin Methylesterase Inhibitor 3 from  Arabidopsis thaliana ."",""doi"":""10.1016/j.tcsw.2022.100080"",""url"":""https://pubmed.ncbi.nlm.nih.gov/36147700/"",""year"":""2022"",""journal"":""Cell surface (Amsterdam, Netherlands)"",""authors"":""Xu F, Gonneau M, Faucher E, Habrylo O, Lefebvre V, Domon JM, Martin M, Sénéchal F, Peaucelle A, Pelloux J, Höfte H."",""matched_aliases"":[""PMEI3""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"