query	query_gene_id	query_protein_id	source_reference	hit_rank	swissprot_acc	swissprot_entry	database_section	target_gene_id	description	organism	homolog_gene_name	percent_identity	alignment_length	query_coverage	evalue	bitscore	confidence	evidence_type	source_db	reference_gene_id	reference_function_zh	reference_function_en	reference_papers_json
LXL04_024103	gene-LXL04_024103	KAL4568490.1	OH-1004	1	Q9MBG8	AAR3_ARATH	Swiss-Prot		Defective in cullin neddylation protein AAR3 OS=Arabidopsis thaliana OX=3702 GN=AAR3 PE=2 SV=1	Arabidopsis thaliana	AAR3	51.689	296	94.097	1.27e-93	281.0	strong_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At3g28970	可能通过将 NEDD8 从 N 端乙酰化的 NEDD8 连接 E2 酶转移到不同的 cullin C 端结构域-RBX 复合物，从而促进所有 cullin 的 neddylation；cullin 的 neddylation 在 SCF 型复合物活性调控中起关键作用（通过相似性推测）。	May contribute to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes; neddylation of cullins play an essential role in the regulation of SCF-type complexes activity (By similarity).	"[{""pmid"":""17905859"",""title"":""Genetic characterization of mutants resistant to the antiauxin p-chlorophenoxyisobutyric acid reveals that AAR3, a gene encoding a DCN1-like protein, regulates responses to the synthetic auxin 2,4-dichlorophenoxyacetic acid in Arabidopsis roots."",""doi"":""10.1104/pp.107.104844"",""url"":""https://pubmed.ncbi.nlm.nih.gov/17905859/"",""year"":""2007"",""journal"":""Plant physiology"",""authors"":""Biswas KK; Ooura C; Higuchi K; Miyazaki Y; Van Nguyen V; Rahman A; Uchimiya H; Kiyosue T; Koshiba T; Tanaka A; Narumi I; Oono Y"",""matched_aliases"":[""AAR3""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false}]"
