query	query_gene_id	query_protein_id	source_reference	hit_rank	swissprot_acc	swissprot_entry	database_section	target_gene_id	description	organism	homolog_gene_name	percent_identity	alignment_length	query_coverage	evalue	bitscore	confidence	evidence_type	source_db	reference_gene_id	reference_function_zh	reference_function_en	reference_papers_json
LXL04_020881	gene-LXL04_020881	KAL4574059.1	OH-1004	1	Q39008	M3K1_ARATH	Swiss-Prot		Mitogen-activated protein kinase kinase kinase 1 OS=Arabidopsis thaliana OX=3702 GN=MEKK1 PE=1 SV=2	Arabidopsis thaliana	MEKK1	37.222	180	91.566	1.14e-20	91.3	moderate_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At4g08500	MEKK1、MKK1/MKK2 和 MPK4 在信号通路中发挥作用，调节响应生物和非生物胁迫的基因表达，并通过负向调节先天免疫在病原体防御中发挥重要作用。	The MEKK1, MKK1/MKK2 and MPK4 function in a signaling pathway that modulates the expression of genes responding to biotic and abiotic stresses and also plays an important role in pathogen defense by negatively regulating innate immunity.	"[{""pmid"":""11875555"",""title"":""MAP kinase signalling cascade in Arabidopsis innate immunity."",""doi"":""10.1038/415977a"",""url"":""https://pubmed.ncbi.nlm.nih.gov/11875555/"",""year"":""2002"",""journal"":""Nature"",""authors"":""Asai T, Tena G, Plotnikova J, Willmann MR, Chiu WL, Gomez-Gomez L, Boller T, Ausubel FM, Sheen J."",""matched_aliases"":[""MEKK1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""15225555"",""title"":""The MKK2 pathway mediates cold and salt stress signaling in Arabidopsis."",""doi"":""10.1016/j.molcel.2004.06.023"",""url"":""https://pubmed.ncbi.nlm.nih.gov/15225555/"",""year"":""2004"",""journal"":""Molecular cell"",""authors"":""Teige M, Scheikl E, Eulgem T, Dóczi R, Ichimura K, Shinozaki K, Dangl JL, Hirt H."",""matched_aliases"":[""MEKK1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""23857079"",""title"":""Phosphorylation of Arabidopsis thaliana MEKK1 via Ca(2+) signaling as a part of the cold stress response."",""doi"":""10.1007/s10265-013-0576-0"",""url"":""https://pubmed.ncbi.nlm.nih.gov/23857079/"",""year"":""2013"",""journal"":""Journal of plant research"",""authors"":""Furuya T, Matsuoka D, Nanmori T."",""matched_aliases"":[""MEKK1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"
LXL04_020881	gene-LXL04_020881	KAL4574059.1	OH-1004	2	O81472	MP3K2_ARATH	Swiss-Prot		Mitogen-activated protein kinase kinase kinase 9 OS=Arabidopsis thaliana OX=3702 GN=MEKK2 PE=1 SV=1	Arabidopsis thaliana	MEKK2	53.488	86	51.807	4.75e-20	89.4	moderate_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At4g08480	触发 SUMM2 介导的免疫反应，包括细胞死亡和防御反应。	Triggers SUMM2-mediated immune responses, including cell death and defense responses.	"[{""pmid"":""22643122"",""title"":""The MEKK1-MKK1/MKK2-MPK4 kinase cascade negatively regulates immunity mediated by a mitogen-activated protein kinase kinase kinase in Arabidopsis."",""doi"":""10.1105/tpc.112.097253"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22643122/"",""year"":""2012"",""journal"":""The Plant cell"",""authors"":""Kong Q, Qu N, Gao M, Zhang Z, Ding X, Yang F, Li Y, Dong OX, Chen S, Li X, Zhang Y."",""matched_aliases"":[""MEKK2"",""SUMM1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""23574009"",""title"":""Glutamate signalling via a MEKK1 kinase-dependent pathway induces changes in Arabidopsis root architecture."",""doi"":""10.1111/tpj.12201"",""url"":""https://pubmed.ncbi.nlm.nih.gov/23574009/"",""year"":""2013"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""Forde BG, Cutler SR, Zaman N, Krysan PJ."",""matched_aliases"":[""MEKK2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""23695980"",""title"":""Deletion of a tandem gene family in Arabidopsis: increased MEKK2 abundance triggers autoimmunity when the MEKK1-MKK1/2-MPK4 signaling cascade is disrupted."",""doi"":""10.1105/tpc.113.112102"",""url"":""https://pubmed.ncbi.nlm.nih.gov/23695980/"",""year"":""2013"",""journal"":""The Plant cell"",""authors"":""Su SH, Bush SM, Zaman N, Stecker K, Sussman MR, Krysan P."",""matched_aliases"":[""MEKK2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"
LXL04_020881	gene-LXL04_020881	KAL4574059.1	OH-1004	5	Q9SZ67	WRK19_ARATH	Swiss-Prot		Probable WRKY transcription factor 19 OS=Arabidopsis thaliana OX=3702 GN=WRKY19 PE=1 SV=1	Arabidopsis thaliana	WRKY19	38.272	162	91.566	1.06e-17	82.8	moderate_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At4g12020	转录因子。	Transcription factor.	[]