query	query_gene_id	query_protein_id	source_reference	hit_rank	swissprot_acc	swissprot_entry	database_section	target_gene_id	description	organism	homolog_gene_name	percent_identity	alignment_length	query_coverage	evalue	bitscore	confidence	evidence_type	source_db	reference_gene_id	reference_function_zh	reference_function_en	reference_papers_json
LXL04_020741	gene-LXL04_020741	KAL4573920.1	OH-1004	4	P46313	FAD6E_ARATH	Swiss-Prot		Delta(12)-fatty-acid desaturase OS=Arabidopsis thaliana OX=3702 GN=FAD2 PE=1 SV=1	Arabidopsis thaliana	FAD2	60.995	382	78.556	2.82e-169	484.0	strong_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At3g12120	ERomega-6 脂肪酸去饱和酶在 18:3 脂肪酸的生物合成中引入第二个双键。	ER (microsomal) omega-6 fatty acid desaturase introduces the second double bond in the biosynthesis of 18:3 fatty acids, important constituents of plant membranes.	"[{""pmid"":""11104757"",""title"":""Consequences of omega -6-oleate desaturase deficiency on lipid dynamics and functional properties of mitochondrial membranes of Arabidopsis thaliana."",""doi"":""10.1074/jbc.m006231200"",""url"":""https://pubmed.ncbi.nlm.nih.gov/11104757/"",""year"":""2001"",""journal"":""The Journal of biological chemistry"",""authors"":""Caiveau O, Fortune D, Cantrel C, Zachowski A, Moreau F."",""matched_aliases"":[""FAD2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""11864983"",""title"":""Desaturation and hydroxylation. Residues 148 and 324 of Arabidopsis FAD2, in addition to substrate chain length, exert a major influence in partitioning of catalytic specificity."",""doi"":""10.1074/jbc.m200231200"",""url"":""https://pubmed.ncbi.nlm.nih.gov/11864983/"",""year"":""2002"",""journal"":""The Journal of biological chemistry"",""authors"":""Broadwater JA, Whittle E, Shanklin J."",""matched_aliases"":[""FAD2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""17507388"",""title"":""Alternative oxidase involvement in cold stress response of Arabidopsis thaliana fad2 and FAD3+ cell suspensions altered in membrane lipid composition."",""doi"":""10.1093/pcp/pcm061"",""url"":""https://pubmed.ncbi.nlm.nih.gov/17507388/"",""year"":""2007"",""journal"":""Plant & cell physiology"",""authors"":""Matos AR, Hourton-Cabassa C, Ciçek D, Rezé N, Arrabaça JD, Zachowski A, Moreau F."",""matched_aliases"":[""FAD2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""22279586"",""title"":""Arabidopsis fatty acid desaturase FAD2 is required for salt tolerance during seed germination and early seedling growth."",""doi"":""10.1371/journal.pone.0030355"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22279586/"",""year"":""2012"",""journal"":""PloS one"",""authors"":""Zhang J, Liu H, Sun J, Li B, Zhu Q, Chen S, Zhang H."",""matched_aliases"":[""FAD2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""7907506"",""title"":""Arabidopsis FAD2 gene encodes the enzyme that is essential for polyunsaturated lipid synthesis."",""doi"":""10.1105/tpc.6.1.147"",""url"":""https://pubmed.ncbi.nlm.nih.gov/7907506/"",""year"":""1994"",""journal"":""The Plant cell"",""authors"":""Okuley J, Lightner J, Feldmann K, Yadav N, Lark E, Browse J."",""matched_aliases"":[""FAD2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""8685264"",""title"":""Functional expression of the extraplastidial Arabidopsis thaliana oleate desaturase gene (FAD2) in Saccharomyces cerevisiae."",""doi"":""10.1104/pp.111.1.223"",""url"":""https://pubmed.ncbi.nlm.nih.gov/8685264/"",""year"":""1996"",""journal"":""Plant physiology"",""authors"":""Covello PS, Reed DW."",""matched_aliases"":[""FAD2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"