query	query_gene_id	query_protein_id	source_reference	hit_rank	swissprot_acc	swissprot_entry	database_section	target_gene_id	description	organism	homolog_gene_name	percent_identity	alignment_length	query_coverage	evalue	bitscore	confidence	evidence_type	source_db	reference_gene_id	reference_function_zh	reference_function_en	reference_papers_json
LXL04_019503	gene-LXL04_019503	KAL4572720.1	OH-1004	2	Q8L746	NPR3_ARATH	Swiss-Prot		Regulatory protein NPR3 OS=Arabidopsis thaliana OX=3702 GN=NPR3 PE=1 SV=1	Arabidopsis thaliana	NPR3	58.505	535	88.591	0.0	626.0	strong_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At5g45110	结合水杨酸（SA）的E3泛素蛋白连接酶复合体（CUL3-RBX1-BTB）底物特异性衔接蛋白，响应SA并介导NPR1泛素化及随后的蛋白酶体降解。	Salicylic acid (SA)-binding substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of NPR1 in response to SA.	"[{""pmid"":""17076807"",""title"":""Negative regulation of defense responses in Arabidopsis by two NPR1 paralogs."",""doi"":""10.1111/j.1365-313x.2006.02903.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/17076807/"",""year"":""2006"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""Zhang Y, Cheng YT, Qu N, Zhao Q, Bi D, Li X."",""matched_aliases"":[""NPR3""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""22699612"",""title"":""NPR3 and NPR4 are receptors for the immune signal salicylic acid in plants."",""doi"":""10.1038/nature11162"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22699612/"",""year"":""2012"",""journal"":""Nature"",""authors"":""Fu ZQ, Yan S, Saleh A, Wang W, Ruble J, Oka N, Mohan R, Spoel SH, Tada Y, Zheng N, Dong X."",""matched_aliases"":[""NPR3""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"
LXL04_019503	gene-LXL04_019503	KAL4572720.1	OH-1004	4	Q5ICL9	NPR4_ARATH	Swiss-Prot		Regulatory protein NPR4 OS=Arabidopsis thaliana OX=3702 GN=NPR4 PE=1 SV=1	Arabidopsis thaliana	NPR4	57.598	533	87.752	0.0	587.0	strong_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At4g19660	结合水杨酸（SA）的E3泛素蛋白连接酶复合体（CUL3-RBX1-BTB）底物特异性衔接蛋白，在缺乏SA时介导NPR1泛素化及随后的蛋白酶体降解。	Salicylic acid (SA)-binding substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of NPR1 in the absence of SA.	"[{""pmid"":""15634206"",""title"":""An Arabidopsis NPR1-like gene, NPR4, is required for disease resistance."",""doi"":""10.1111/j.1365-313x.2004.02296.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/15634206/"",""year"":""2005"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""Liu G, Holub EB, Alonso JM, Ecker JR, Fobert PR."",""matched_aliases"":[""NPR4""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""17076807"",""title"":""Negative regulation of defense responses in Arabidopsis by two NPR1 paralogs."",""doi"":""10.1111/j.1365-313x.2006.02903.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/17076807/"",""year"":""2006"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""Zhang Y, Cheng YT, Qu N, Zhao Q, Bi D, Li X."",""matched_aliases"":[""NPR4""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""22699612"",""title"":""NPR3 and NPR4 are receptors for the immune signal salicylic acid in plants."",""doi"":""10.1038/nature11162"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22699612/"",""year"":""2012"",""journal"":""Nature"",""authors"":""Fu ZQ, Yan S, Saleh A, Wang W, Ruble J, Oka N, Mohan R, Spoel SH, Tada Y, Zheng N, Dong X."",""matched_aliases"":[""NPR4""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""32788727"",""title"":""Structural basis of salicylic acid perception by Arabidopsis NPR proteins."",""doi"":""10.1038/s41586-020-2596-y"",""url"":""https://pubmed.ncbi.nlm.nih.gov/32788727/"",""year"":""2020"",""journal"":""Nature"",""authors"":""Wang W, Withers J, Li H, Zwack PJ, Rusnac DV, Shi H, Liu L, Yan S, Hinds TR, Guttman M, Dong X, Zheng N."",""matched_aliases"":[""NPR4""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"
LXL04_019503	gene-LXL04_019503	KAL4572720.1	OH-1004	3	Q0JJ01	NPR2_ORYSJ	Swiss-Prot		BTB/POZ domain and ankyrin repeat-containing protein NPR2 OS=Oryza sativa subsp. japonica OX=39947 GN=NPR2 PE=1 SV=1	Oryza sativa subsp. japonica	NPR2	55.935	556	89.765	0.0	603.0	strong_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	Os01g0767900	水杨酸（SA）结合的底物特异性适配器，属于E3泛素蛋白连接酶复合物（CUL3-RBX1-BTB），介导目标蛋白的泛素化及随后通过蛋白酶体降解（通过相似性预测）。	Salicylic acid (SA)-binding substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).	"[{""pmid"":""17309686"",""title"":""Functional analysis of rice NPR1-like genes reveals that OsNPR1/NH1 is the rice orthologue conferring disease resistance with enhanced herbivore susceptibility."",""doi"":""10.1111/j.1467-7652.2007.00243.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/17309686/"",""year"":""2007"",""journal"":""Plant biotechnology journal"",""authors"":""Yuan Y; Zhong S; Li Q; Zhu Z; Lou Y; Wang L; Wang J; Wang M; Li Q; Yang D; He Z"",""matched_aliases"":[""OsNPR2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false}]"
LXL04_019503	gene-LXL04_019503	KAL4572720.1	OH-1004	5	Q75HA6	NPR3_ORYSJ	Swiss-Prot		BTB/POZ domain and ankyrin repeat-containing protein NPR3 OS=Oryza sativa subsp. japonica OX=39947 GN=NPR3 PE=1 SV=1	Oryza sativa subsp. japonica	NPR3	51.927	545	88.591	0.0	534.0	strong_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	Os03g0667100	水杨酸（SA）结合的底物特异性适配器，属于E3泛素蛋白连接酶复合物（CUL3-RBX1-BTB），介导目标蛋白的泛素化及随后通过蛋白酶体降解（通过相似性预测）。	Salicylic acid (SA)-binding substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).	"[{""pmid"":""17309686"",""title"":""Functional analysis of rice NPR1-like genes reveals that OsNPR1/NH1 is the rice orthologue conferring disease resistance with enhanced herbivore susceptibility."",""doi"":""10.1111/j.1467-7652.2007.00243.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/17309686/"",""year"":""2007"",""journal"":""Plant biotechnology journal"",""authors"":""Yuan Y; Zhong S; Li Q; Zhu Z; Lou Y; Wang L; Wang J; Wang M; Li Q; Yang D; He Z"",""matched_aliases"":[""OsNPR3""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false}]"