query	query_gene_id	query_protein_id	source_reference	hit_rank	swissprot_acc	swissprot_entry	database_section	target_gene_id	description	organism	homolog_gene_name	percent_identity	alignment_length	query_coverage	evalue	bitscore	confidence	evidence_type	source_db	reference_gene_id	reference_function_zh	reference_function_en	reference_papers_json
LXL04_017609	gene-LXL04_017609	KAL4581395.1	OH-1004	1	F4K3G5	EDM2_ARATH	Swiss-Prot		Protein ENHANCED DOWNY MILDEW 2 OS=Arabidopsis thaliana OX=3702 GN=EDM2 PE=1 SV=1	Arabidopsis thaliana	EDM2	60.0	310	30.156	2.34e-119	400.0	weak_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At5g55390	细胞抗沉默因子和基因组DNA甲基化模式的调控因子，参与染色质状态的调控。	Cellular antisilencing factor and regulator of genome DNA methylation patterns involved in the regulation of chromatin states.	"[{""pmid"":""17253987"",""title"":""EDM2 is required for RPP7-dependent disease resistance in Arabidopsis and affects RPP7 transcript levels."",""doi"":""10.1111/j.1365-313x.2006.02999.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/17253987/"",""year"":""2007"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""Eulgem T; Tsuchiya T; Wang XJ; Beasley B; Cuzick A; Tör M; Zhu T; McDowell JM; Holub E; Dangl JL"",""matched_aliases"":[""EDM2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""20149132"",""title"":""The Arabidopsis defense component EDM2 affects the floral transition in an FLC-dependent manner."",""doi"":""10.1111/j.1365-313x.2010.04169.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/20149132/"",""year"":""2010"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""Tsuchiya T, Eulgem T."",""matched_aliases"":[""EDM2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""20840782"",""title"":""Co-option of EDM2 to distinct regulatory modules in Arabidopsis thaliana development."",""doi"":""10.1186/1471-2229-10-203"",""url"":""https://pubmed.ncbi.nlm.nih.gov/20840782/"",""year"":""2010"",""journal"":""BMC plant biology"",""authors"":""Tsuchiya T, Eulgem T."",""matched_aliases"":[""EDM2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""21830950"",""title"":""EMSY-like genes are required for full RPP7-mediated race-specific immunity and basal defense in Arabidopsis."",""doi"":""10.1094/mpmi-05-11-0123"",""url"":""https://pubmed.ncbi.nlm.nih.gov/21830950/"",""year"":""2011"",""journal"":""Molecular plant-microbe interactions : MPMI"",""authors"":""Tsuchiya T; Eulgem T"",""matched_aliases"":[""EDM2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""23609044"",""title"":""Mutations in EDM2 selectively affect silencing states of transposons and induce plant developmental plasticity."",""doi"":""10.1038/srep01701"",""url"":""https://pubmed.ncbi.nlm.nih.gov/23609044/"",""year"":""2013"",""journal"":""Scientific reports"",""authors"":""Tsuchiya T; Eulgem T"",""matched_aliases"":[""EDM2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""23976921"",""title"":""Antagonistic regulation of flowering time through distinct regulatory subunits of protein phosphatase 2A."",""doi"":""10.1371/journal.pone.0067987"",""url"":""https://pubmed.ncbi.nlm.nih.gov/23976921/"",""year"":""2013"",""journal"":""PloS one"",""authors"":""Heidari B; Nemie-Feyissa D; Kangasjärvi S; Lillo C"",""matched_aliases"":[""EDM2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""24248388"",""title"":""Arabidopsis EDM2 promotes IBM1 distal polyadenylation and regulates genome DNA methylation patterns."",""doi"":""10.1073/pnas.1320106110"",""url"":""https://pubmed.ncbi.nlm.nih.gov/24248388/"",""year"":""2014"",""journal"":""Proceedings of the National Academy of Sciences of the United States of America"",""authors"":""Lei M; La H; Lu K; Wang P; Miki D; Ren Z; Duan CG; Wang X; Tang K; Zeng L; Yang L; Zhang H; Nie W; Liu P; Zhou J; Liu R; Zhong Y; Liu D; Zhu JK"",""matched_aliases"":[""EDM2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""27697902"",""title"":""Demethylation of ERECTA receptor genes by IBM1 histone demethylase affects stomatal development."",""doi"":""10.1242/dev.129932"",""url"":""https://pubmed.ncbi.nlm.nih.gov/27697902/"",""year"":""2016"",""journal"":""Development (Cambridge, England)"",""authors"":""Wang Y; Xue X; Zhu JK; Dong J"",""matched_aliases"":[""EDM2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""28808009"",""title"":""A protein complex regulates RNA processing of intronic heterochromatin-containing genes in  Arabidopsis ."",""doi"":""10.1073/pnas.1710683114"",""url"":""https://pubmed.ncbi.nlm.nih.gov/28808009/"",""year"":""2017"",""journal"":""Proceedings of the National Academy of Sciences of the United States of America"",""authors"":""Duan CG, Wang X, Zhang L, Xiong X, Zhang Z, Tang K, Pan L, Hsu CC, Xu H, Tao WA, Zhang H, Zhu JK."",""matched_aliases"":[""EDM2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""30407670"",""title"":""The Arabidopsis RRM domain protein EDM3 mediates race-specific disease resistance by controlling H3K9me2-dependent alternative polyadenylation of RPP7 immune receptor transcripts."",""doi"":""10.1111/tpj.14148"",""url"":""https://pubmed.ncbi.nlm.nih.gov/30407670/"",""year"":""2019"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""Lai Y; Cuzick A; Lu XM; Wang J; Katiyar N; Tsuchiya T; Le Roch K; McDowell JM; Holub E; Eulgem T"",""matched_aliases"":[""EDM2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""32925902"",""title"":""The Arabidopsis PHD-finger protein EDM2 has multiple roles in balancing NLR immune receptor gene expression."",""doi"":""10.1371/journal.pgen.1008993"",""url"":""https://pubmed.ncbi.nlm.nih.gov/32925902/"",""year"":""2020"",""journal"":""PLoS genetics"",""authors"":""Lai Y; Lu XM; Daron J; Pan S; Wang J; Wang W; Tsuchiya T; Holub E; McDowell JM; Slotkin RK; Le Roch KG; Eulgem T"",""matched_aliases"":[""EDM2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""33438356"",""title"":""Genome-wide distribution and functions of the AAE complex in epigenetic regulation in Arabidopsis."",""doi"":""10.1111/jipb.13068"",""url"":""https://pubmed.ncbi.nlm.nih.gov/33438356/"",""year"":""2021"",""journal"":""Journal of integrative plant biology"",""authors"":""Zhang YZ, Lin J, Ren Z, Chen CX, Miki D, Xie SS, Zhang J, Chang YN, Jiang J, Yan J, Li QQ, Zhu JK, Duan CG."",""matched_aliases"":[""EDM2""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"