query	query_gene_id	query_protein_id	source_reference	hit_rank	swissprot_acc	swissprot_entry	database_section	target_gene_id	description	organism	homolog_gene_name	percent_identity	alignment_length	query_coverage	evalue	bitscore	confidence	evidence_type	source_db	reference_gene_id	reference_function_zh	reference_function_en	reference_papers_json
LXL04_016972	gene-LXL04_016972	KAL4580770.1	OH-1004	1	Q9FVW4	RENT3_ARATH	Swiss-Prot		Regulator of nonsense transcripts UPF3 OS=Arabidopsis thaliana OX=3702 GN=UPF3 PE=1 SV=1	Arabidopsis thaliana	UPF3	44.553	514	100.0	1.18e-107	331.0	moderate_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At1g33980	在核膜胞质侧招募UPF2，随后形成UPF1-UPF2-UPF3监视复合体（包括结合于阻滞核糖体释放因子的UPF1），据信激活NMD。	Recruits UPF2 at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD.	"[{""pmid"":""16098107"",""title"":""UPF3 suppresses aberrant spliced mRNA in Arabidopsis."",""doi"":""10.1111/j.1365-313x.2005.02473.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/16098107/"",""year"":""2005"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""Hori K; Watanabe Y"",""matched_aliases"":[""AtUPF3"",""UPF3""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""19181858"",""title"":""Genome-wide suppression of aberrant mRNA-like noncoding RNAs by NMD in Arabidopsis."",""doi"":""10.1073/pnas.0808902106"",""url"":""https://pubmed.ncbi.nlm.nih.gov/19181858/"",""year"":""2009"",""journal"":""Proceedings of the National Academy of Sciences of the United States of America"",""authors"":""Kurihara Y, Matsui A, Hanada K, Kawashima M, Ishida J, Morosawa T, Tanaka M, Kaminuma E, Mochizuki Y, Matsushima A, Toyoda T, Shinozaki K, Seki M."",""matched_aliases"":[""UPF3""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""19863731"",""title"":""Extensive coupling of alternative splicing of pre-mRNAs of serine/arginine (SR) genes with nonsense-mediated decay."",""doi"":""10.1111/j.1469-8137.2009.03065.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/19863731/"",""year"":""2010"",""journal"":""The New phytologist"",""authors"":""Palusa SG; Reddy AS"",""matched_aliases"":[""UPF3""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""22025558"",""title"":""Nonsense-mediated mRNA decay factors, UPF1 and UPF3, contribute to plant defense."",""doi"":""10.1093/pcp/pcr144"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22025558/"",""year"":""2011"",""journal"":""Plant & cell physiology"",""authors"":""Jeong HJ, Kim YJ, Kim SH, Kim YH, Lee IJ, Kim YK, Shin JS."",""matched_aliases"":[""UPF3""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""22127866"",""title"":""Alternative splicing and nonsense-mediated decay modulate expression of important regulatory genes in Arabidopsis."",""doi"":""10.1093/nar/gkr932"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22127866/"",""year"":""2012"",""journal"":""Nucleic acids research"",""authors"":""Kalyna M, Simpson CG, Syed NH, Lewandowska D, Marquez Y, Kusenda B, Marshall J, Fuller J, Cardle L, McNicol J, Dinh HQ, Barta A, Brown JW."",""matched_aliases"":[""UPF3""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""22353561"",""title"":""Arabidopsis plants having defects in nonsense-mediated mRNA decay factors UPF1, UPF2, and UPF3 show photoperiod-dependent phenotypes in development and stress responses."",""doi"":""10.1111/j.1744-7909.2012.01093.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22353561/"",""year"":""2012"",""journal"":""Journal of integrative plant biology"",""authors"":""Shi C, Baldwin IT, Wu J."",""matched_aliases"":[""UPF3""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"