query	query_gene_id	query_protein_id	source_reference	hit_rank	swissprot_acc	swissprot_entry	database_section	target_gene_id	description	organism	homolog_gene_name	percent_identity	alignment_length	query_coverage	evalue	bitscore	confidence	evidence_type	source_db	reference_gene_id	reference_function_zh	reference_function_en	reference_papers_json
LXL04_011137	gene-LXL04_011137	KAL4586501.1	OH-1004	1	Q6NQI8	LOH3_ARATH	Swiss-Prot		Ceramide synthase 1 LOH3 OS=Arabidopsis thaliana OX=3702 GN=LOH3 PE=1 SV=2	Arabidopsis thaliana	LOH3	74.627	268	64.578	2.69e-145	418.0	moderate_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At1g13580	对植物生长至关重要，促进根分生组织中的细胞分裂。	Essential for plant growth, promotes cell division in root meristems.	"[{""pmid"":""21883234"",""title"":""Disruption of the ceramide synthase LOH1 causes spontaneous cell death in Arabidopsis thaliana."",""doi"":""10.1111/j.1469-8137.2011.03852.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/21883234/"",""year"":""2011"",""journal"":""The New phytologist"",""authors"":""Ternes P; Feussner K; Werner S; Lerche J; Iven T; Heilmann I; Riezman H; Feussner I"",""matched_aliases"":[""LOH3""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""25822663"",""title"":""Unsaturation of very-long-chain ceramides protects plant from hypoxia-induced damages by modulating ethylene signaling in Arabidopsis."",""doi"":""10.1371/journal.pgen.1005143"",""url"":""https://pubmed.ncbi.nlm.nih.gov/25822663/"",""year"":""2015"",""journal"":""PLoS genetics"",""authors"":""Xie LJ, Chen QF, Chen MX, Yu LJ, Huang L, Chen L, Wang FZ, Xia FN, Zhu TR, Wu JX, Yin J, Liao B, Shi J, Zhang JH, Aharoni A, Yao N, Shu W, Xiao S."",""matched_aliases"":[""LOH3""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""26276842"",""title"":""Overexpression of Arabidopsis Ceramide Synthases Differentially Affects Growth, Sphingolipid Metabolism, Programmed Cell Death, and Mycotoxin Resistance."",""doi"":""10.1104/pp.15.00987"",""url"":""https://pubmed.ncbi.nlm.nih.gov/26276842/"",""year"":""2015"",""journal"":""Plant physiology"",""authors"":""Luttgeharm KD; Chen M; Mehra A; Cahoon RE; Markham JE; Cahoon EB"",""matched_aliases"":[""LOH3""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""26635357"",""title"":""Substrate specificity, kinetic properties and inhibition by fumonisin B1 of ceramide synthase isoforms from Arabidopsis."",""doi"":""10.1042/bj20150824"",""url"":""https://pubmed.ncbi.nlm.nih.gov/26635357/"",""year"":""2016"",""journal"":""The Biochemical journal"",""authors"":""Luttgeharm KD; Cahoon EB; Markham JE"",""matched_aliases"":[""LOH3""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false}]"
LXL04_011137	gene-LXL04_011137	KAL4586501.1	OH-1004	7	Q9LDF2	LOH1_ARATH	Swiss-Prot		Ceramide synthase LOH1 OS=Arabidopsis thaliana OX=3702 GN=LOH1 PE=1 SV=1	Arabidopsis thaliana	LOH1	72.177	248	59.518	1.61e-132	386.0	moderate_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At3g25540	对植物生长至关重要，促进根分生组织中的细胞分裂。	Essential for plant growth, promotes cell division in root meristems.	"[{""pmid"":""21883234"",""title"":""Disruption of the ceramide synthase LOH1 causes spontaneous cell death in Arabidopsis thaliana."",""doi"":""10.1111/j.1469-8137.2011.03852.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/21883234/"",""year"":""2011"",""journal"":""The New phytologist"",""authors"":""Ternes P; Feussner K; Werner S; Lerche J; Iven T; Heilmann I; Riezman H; Feussner I"",""matched_aliases"":[""LOH1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""25822663"",""title"":""Unsaturation of very-long-chain ceramides protects plant from hypoxia-induced damages by modulating ethylene signaling in Arabidopsis."",""doi"":""10.1371/journal.pgen.1005143"",""url"":""https://pubmed.ncbi.nlm.nih.gov/25822663/"",""year"":""2015"",""journal"":""PLoS genetics"",""authors"":""Xie LJ, Chen QF, Chen MX, Yu LJ, Huang L, Chen L, Wang FZ, Xia FN, Zhu TR, Wu JX, Yin J, Liao B, Shi J, Zhang JH, Aharoni A, Yao N, Shu W, Xiao S."",""matched_aliases"":[""LOH1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""26276842"",""title"":""Overexpression of Arabidopsis Ceramide Synthases Differentially Affects Growth, Sphingolipid Metabolism, Programmed Cell Death, and Mycotoxin Resistance."",""doi"":""10.1104/pp.15.00987"",""url"":""https://pubmed.ncbi.nlm.nih.gov/26276842/"",""year"":""2015"",""journal"":""Plant physiology"",""authors"":""Luttgeharm KD; Chen M; Mehra A; Cahoon RE; Markham JE; Cahoon EB"",""matched_aliases"":[""At3g25540"",""LOH1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""26635357"",""title"":""Substrate specificity, kinetic properties and inhibition by fumonisin B1 of ceramide synthase isoforms from Arabidopsis."",""doi"":""10.1042/bj20150824"",""url"":""https://pubmed.ncbi.nlm.nih.gov/26635357/"",""year"":""2016"",""journal"":""The Biochemical journal"",""authors"":""Luttgeharm KD; Cahoon EB; Markham JE"",""matched_aliases"":[""LOH1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false}]"
LXL04_011137	gene-LXL04_011137	KAL4586501.1	OH-1004	5	Q6EUN0	ASCL1_ORYSJ	Swiss-Prot		ASC1-like protein 1 OS=Oryza sativa subsp. japonica OX=39947 GN=Os02g0581300 PE=2 SV=1	Oryza sativa subsp. japonica	Os02g0581300	69.776	268	64.578	7.18e-133	387.0	moderate_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	Os02g0581300	通过恢复鞘脂生物合成介导对鞘氨醇类似霉菌毒素 (SAMs) 的抗性。	Mediates resistance to sphinganine-analog mycotoxins (SAMs) by restoring the sphingolipid biosynthesis.	[]
LXL04_011137	gene-LXL04_011137	KAL4586501.1	OH-1004	9	Q6YWS8	ASCL2_ORYSJ	Swiss-Prot		ASC1-like protein 2 OS=Oryza sativa subsp. japonica OX=39947 GN=Os02g0728300 PE=3 SV=2	Oryza sativa subsp. japonica	Os02g0728300	64.729	258	62.169	2.82e-117	347.0	moderate_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	Os02g0728300	通过恢复鞘脂生物合成介导对鞘氨醇类似霉菌毒素 (SAMs) 的抗性。	Mediates resistance to sphinganine-analog mycotoxins (SAMs) by restoring the sphingolipid biosynthesis.	[]