query	query_gene_id	query_protein_id	source_reference	hit_rank	swissprot_acc	swissprot_entry	database_section	target_gene_id	description	organism	homolog_gene_name	percent_identity	alignment_length	query_coverage	evalue	bitscore	confidence	evidence_type	source_db	reference_gene_id	reference_function_zh	reference_function_en	reference_papers_json
LXL04_009589	gene-LXL04_009589	KAL4584976.1	OH-1004	1	F4JCQ3	DG783_ARATH	Swiss-Prot		Putative DNA glycosylase At3g47830 OS=Arabidopsis thaliana OX=3702 GN=At3g47830 PE=3 SV=1	Arabidopsis thaliana	At3g47830	59.459	259	40.063	1.65e-106	327.0	weak_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At3g47830	推定 DNA 糖苷酶 At3g47830。	Putative DNA glycosylase At3g47830.	[]
LXL04_009589	gene-LXL04_009589	KAL4584976.1	OH-1004	4	Q9SJQ6	ROS1_ARATH	Swiss-Prot		DNA glycosylase/AP lyase ROS1 OS=Arabidopsis thaliana OX=3702 GN=ROS1 PE=1 SV=2	Arabidopsis thaliana	ROS1	30.058	173	24.413	7.52e-14	79.0	weak_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At2g36490	双功能 DNA 糖基化酶/裂解酶，可切除 5-甲基胞嘧啶 (5-meC) 和 5-羟甲基胞嘧啶 (5-hmeC)，留下一个嘧啶缺失 (AP) 位点，随后由裂解酶活性切割。	Bifunctional DNA glycosylase/lyase, which excises 5-methylcytosine (5-meC) and 5-hydroxymethylcytosine (5-hmeC), leaving an apyrimidinic (AP) site that is subsequently incised by the lyase activity.	"[{""pmid"":""12526807"",""title"":""ROS1, a repressor of transcriptional gene silencing in Arabidopsis, encodes a DNA glycosylase/lyase."",""doi"":""10.1016/s0092-8674(02)01133-9"",""url"":""https://pubmed.ncbi.nlm.nih.gov/12526807/"",""year"":""2002"",""journal"":""Cell"",""authors"":""Gong Z; Morales-Ruiz T; Ariza RR; Roldán-Arjona T; David L; Zhu JK"",""matched_aliases"":[""ROS1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""16624880"",""title"":""DEMETER and REPRESSOR OF SILENCING 1 encode 5-methylcytosine DNA glycosylases."",""doi"":""10.1073/pnas.0601109103"",""url"":""https://pubmed.ncbi.nlm.nih.gov/16624880/"",""year"":""2006"",""journal"":""Proceedings of the National Academy of Sciences of the United States of America"",""authors"":""Morales-Ruiz T; Ortega-Galisteo AP; Ponferrada-Marín MI; Martínez-Macías MI; Ariza RR; Roldán-Arjona T"",""matched_aliases"":[""ROS1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""19443451"",""title"":""ROS1 5-methylcytosine DNA glycosylase is a slow-turnover catalyst that initiates DNA demethylation in a distributive fashion."",""doi"":""10.1093/nar/gkp390"",""url"":""https://pubmed.ncbi.nlm.nih.gov/19443451/"",""year"":""2009"",""journal"":""Nucleic acids research"",""authors"":""Ponferrada-Marín MI; Roldán-Arjona T; Ariza RR"",""matched_aliases"":[""ROS1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""20489198"",""title"":""Methylation-independent DNA binding modulates specificity of Repressor of Silencing 1 (ROS1) and facilitates demethylation in long substrates."",""doi"":""10.1074/jbc.m110.124578"",""url"":""https://pubmed.ncbi.nlm.nih.gov/20489198/"",""year"":""2010"",""journal"":""The Journal of biological chemistry"",""authors"":""Ponferrada-Marín MI; Martínez-Macías MI; Morales-Ruiz T; Roldán-Arjona T; Ariza RR"",""matched_aliases"":[""ROS1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""24155752"",""title"":""DDM1 and ROS1 have a role in UV-B induced- and oxidative DNA damage in A. thaliana."",""doi"":""10.3389/fpls.2013.00420"",""url"":""https://pubmed.ncbi.nlm.nih.gov/24155752/"",""year"":""2013"",""journal"":""Frontiers in plant science"",""authors"":""Qüesta JI; Fina JP; Casati P"",""matched_aliases"":[""ROS1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""25228464"",""title"":""AP endonucleases process 5-methylcytosine excision intermediates during active DNA demethylation in Arabidopsis."",""doi"":""10.1093/nar/gku834"",""url"":""https://pubmed.ncbi.nlm.nih.gov/25228464/"",""year"":""2014"",""journal"":""Nucleic acids research"",""authors"":""Lee J, Jang H, Shin H, Choi WL, Mok YG, Huh JH."",""matched_aliases"":[""ROS1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""25240767"",""title"":""The carboxy-terminal domain of ROS1 is essential for 5-methylcytosine DNA glycosylase activity."",""doi"":""10.1016/j.jmb.2014.09.010"",""url"":""https://pubmed.ncbi.nlm.nih.gov/25240767/"",""year"":""2014"",""journal"":""Journal of molecular biology"",""authors"":""Hong S; Hashimoto H; Kow YW; Zhang X; Cheng X"",""matched_aliases"":[""ROS1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false}]"
LXL04_009589	gene-LXL04_009589	KAL4584976.1	OH-1004	3	C7IW64	ROS1A_ORYSJ	Swiss-Prot		Protein ROS1A OS=Oryza sativa subsp. japonica OX=39947 GN=ROS1A PE=1 SV=2	Oryza sativa subsp. japonica	ROS1A	26.054	261	38.185	3.15e-14	80.5	weak_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	Os01g0218032	双功能DNA糖基化酶/裂解酶，可切除5-甲基胞嘧啶 (5-meC) 和5-羟甲基胞嘧啶 (5-hmeC)，产生一个嘧啶缺位(AP)位点，随后该位点由裂解酶活性切开（可能）。	Bifunctional DNA glycosylase/lyase, which excises 5-methylcytosine (5-meC) and 5-hydroxymethylcytosine (5-hmeC), leaving an apyrimidinic (AP) site that is subsequently incised by the lyase activity (Probable).	"[{""pmid"":""22448681"",""title"":""A null mutation of ROS1a for DNA demethylation in rice is not transmittable to progeny."",""doi"":""10.1111/j.1365-313x.2012.05009.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22448681/"",""year"":""2012"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""Ono A; Yamaguchi K; Fukada-Tanaka S; Terada R; Mitsui T; Iida S"",""matched_aliases"":[""ROS1A""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""30275307"",""title"":""Mutations in the DNA demethylase OsROS1 result in a thickened aleurone and improved nutritional value in rice grains."",""doi"":""10.1073/pnas.1806304115"",""url"":""https://pubmed.ncbi.nlm.nih.gov/30275307/"",""year"":""2018"",""journal"":""Proceedings of the National Academy of Sciences of the United States of America"",""authors"":""Liu J; Wu X; Yao X; Yu R; Larkin PJ; Liu CM"",""matched_aliases"":[""OsROS1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false}]"
LXL04_009589	gene-LXL04_009589	KAL4584976.1	OH-1004	5	B8YIE8	ROS1C_ORYSJ	Swiss-Prot		Protein ROS1C OS=Oryza sativa subsp. japonica OX=39947 GN=ROS1C PE=2 SV=2	Oryza sativa subsp. japonica	ROS1C	30.636	173	24.413	1.66e-13	78.2	weak_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	Os05g0445900	双功能 DNA 糖基化酶/裂解酶，可切除 5-甲基胞嘧啶 (5-meC) 和 5-羟甲基胞嘧啶 (5-hmeC)，留下一个嘧啶缺失 (AP) 位点，随后由裂解酶活性切割。	Bifunctional DNA glycosylase/lyase, which excises 5-methylcytosine (5-meC) and 5-hydroxymethylcytosine (5-hmeC), leaving an apyrimidinic (AP) site that is subsequently incised by the lyase activity.	"[{""pmid"":""21896764"",""title"":""A 5-methylcytosine DNA glycosylase/lyase demethylates the retrotransposon Tos17 and promotes its transposition in rice."",""doi"":""10.1073/pnas.1112704108"",""url"":""https://pubmed.ncbi.nlm.nih.gov/21896764/"",""year"":""2011"",""journal"":""Proceedings of the National Academy of Sciences of the United States of America"",""authors"":""La H; Ding B; Mishra GP; Zhou B; Yang H; Bellizzi Mdel R; Chen S; Meyers BC; Peng Z; Zhu JK; Wang GL"",""matched_aliases"":[""DNG701""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false}]"