query	query_gene_id	query_protein_id	source_reference	hit_rank	swissprot_acc	swissprot_entry	database_section	target_gene_id	description	organism	homolog_gene_name	percent_identity	alignment_length	query_coverage	evalue	bitscore	confidence	evidence_type	source_db	reference_gene_id	reference_function_zh	reference_function_en	reference_papers_json
LXL04_002480	gene-LXL04_002480	KAL4589572.1	OH-1004	1	Q9FJV0	M2K6_ARATH	Swiss-Prot		Mitogen-activated protein kinase kinase 6 OS=Arabidopsis thaliana OX=3702 GN=MKK6 PE=1 SV=1	Arabidopsis thaliana	MKK6	79.885	348	70.747	0.0	591.0	strong_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At5g56580	ANPs-MKK6-MPK4 模块参与减数分裂和有丝分裂过程中植物胞质分裂的调节。	The ANPs-MKK6-MPK4 module is involved in the regulation of plant cytokinesis during meiosis and mitosis.	"[{""pmid"":""12704083"",""title"":""NQK1/NtMEK1 is a MAPKK that acts in the NPK1 MAPKKK-mediated MAPK cascade and is required for plant cytokinesis."",""doi"":""10.1101/gad.1071103"",""url"":""https://pubmed.ncbi.nlm.nih.gov/12704083/"",""year"":""2003"",""journal"":""Genes & development"",""authors"":""Soyano T, Nishihama R, Morikiyo K, Ishikawa M, Machida Y."",""matched_aliases"":[""ANQ1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""15474000"",""title"":""The Arabidopsis thaliana MEK AtMKK6 activates the MAP kinase AtMPK13."",""doi"":""10.1016/j.febslet.2004.08.051"",""url"":""https://pubmed.ncbi.nlm.nih.gov/15474000/"",""year"":""2004"",""journal"":""FEBS letters"",""authors"":""Melikant B, Giuliani C, Halbmayer-Watzina S, Limmongkon A, Heberle-Bors E, Wilson C."",""matched_aliases"":[""AtMKK6""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""20802223"",""title"":""HINKEL kinesin, ANP MAPKKKs and MKK6/ANQ MAPKK, which phosphorylates and activates MPK4 MAPK, constitute a pathway that is required for cytokinesis in Arabidopsis thaliana."",""doi"":""10.1093/pcp/pcq135"",""url"":""https://pubmed.ncbi.nlm.nih.gov/20802223/"",""year"":""2010"",""journal"":""Plant & cell physiology"",""authors"":""Takahashi Y, Soyano T, Kosetsu K, Sasabe M, Machida Y."",""matched_aliases"":[""MKK6""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""21098735"",""title"":""The MAP kinase MPK4 is required for cytokinesis in Arabidopsis thaliana."",""doi"":""10.1105/tpc.110.077164"",""url"":""https://pubmed.ncbi.nlm.nih.gov/21098735/"",""year"":""2010"",""journal"":""The Plant cell"",""authors"":""Kosetsu K, Matsunaga S, Nakagami H, Colcombet J, Sasabe M, Soyano T, Takahashi Y, Hirt H, Machida Y."",""matched_aliases"":[""MKK6""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""21575092"",""title"":""AtMPK4 is required for male-specific meiotic cytokinesis in Arabidopsis."",""doi"":""10.1111/j.1365-313x.2011.04642.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/21575092/"",""year"":""2011"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""Zeng Q, Chen JG, Ellis BE."",""matched_aliases"":[""ANQ1"",""AtMKK6"",""MKK6""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""21904115"",""title"":""AtMKK6 and AtMPK13 are required for lateral root formation in Arabidopsis."",""doi"":""10.4161/psb.6.10.17089"",""url"":""https://pubmed.ncbi.nlm.nih.gov/21904115/"",""year"":""2011"",""journal"":""Plant signaling & behavior"",""authors"":""Zeng Q, Sritubtim S, Ellis BE."",""matched_aliases"":[""AtMKK6""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"
LXL04_002480	gene-LXL04_002480	KAL4589572.1	OH-1004	2	Q5QN75	M2K1_ORYSJ	Swiss-Prot		Mitogen-activated protein kinase kinase 1 OS=Oryza sativa subsp. japonica OX=39947 GN=MKK1 PE=1 SV=1	Oryza sativa subsp. japonica	MKK1	72.881	354	71.784	0.0	533.0	strong_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	Os01g0510100	丝裂原活化蛋白激酶激酶1。	Mitogen-activated protein kinase kinase 1.	[]