query	query_gene_id	query_protein_id	source_reference	hit_rank	swissprot_acc	swissprot_entry	database_section	target_gene_id	description	organism	homolog_gene_name	percent_identity	alignment_length	query_coverage	evalue	bitscore	confidence	evidence_type	source_db	reference_gene_id	reference_function_zh	reference_function_en	reference_papers_json
LXL04_002409	gene-LXL04_002409	KAL4589502.1	OH-1004	3	P93002	NPR1_ARATH	Swiss-Prot		Regulatory protein NPR1 OS=Arabidopsis thaliana OX=3702 GN=NPR1 PE=1 SV=1	Arabidopsis thaliana	NPR1	50.568	528	55.413	2.75e-169	509.0	moderate_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At1g64280	水杨酸（SA）结合的底物特异性适配器，属于E3泛素蛋白连接酶复合物（CUL3-RBX1-BTB），介导目标蛋白的泛素化及随后通过蛋白酶体降解（通过相似性预测）。	Salicylic acid (SA)-binding substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).	"[{""pmid"":""11607555"",""title"":""Arabidopsis signal transduction mutant defective in chemically and biologically induced disease resistance."",""doi"":""10.1073/pnas.92.14.6602"",""url"":""https://pubmed.ncbi.nlm.nih.gov/11607555/"",""year"":""1995"",""journal"":""Proceedings of the National Academy of Sciences of the United States of America"",""authors"":""Delaney TP; Friedrich L; Ryals JA"",""matched_aliases"":[""NIM1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""12615947"",""title"":""NPR1 modulates cross-talk between salicylate- and jasmonate-dependent defense pathways through a novel function in the cytosol."",""doi"":""10.1105/tpc.009159"",""url"":""https://pubmed.ncbi.nlm.nih.gov/12615947/"",""year"":""2003"",""journal"":""The Plant cell"",""authors"":""Spoel SH; Koornneef A; Claessens SM; Korzelius JP; Van Pelt JA; Mueller MJ; Buchala AJ; Métraux JP; Brown R; Kazan K; Van Loon LC; Dong X; Pieterse CM"",""matched_aliases"":[""NPR1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""12897257"",""title"":""Salicylic acid and NPR1 induce the recruitment of trans-activating TGA factors to a defense gene promoter in Arabidopsis."",""doi"":""10.1105/tpc.012211"",""url"":""https://pubmed.ncbi.nlm.nih.gov/12897257/"",""year"":""2003"",""journal"":""The Plant cell"",""authors"":""Johnson C, Boden E, Arias J."",""matched_aliases"":[""NPR1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""12953119"",""title"":""The Arabidopsis NPR1 disease resistance protein is a novel cofactor that confers redox regulation of DNA binding activity to the basic domain/leucine zipper transcription factor TGA1."",""doi"":""10.1105/tpc.012849"",""url"":""https://pubmed.ncbi.nlm.nih.gov/12953119/"",""year"":""2003"",""journal"":""The Plant cell"",""authors"":""Després C; Chubak C; Rochon A; Clark R; Bethune T; Desveaux D; Fobert PR"",""matched_aliases"":[""NPR1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""22699612"",""title"":""NPR3 and NPR4 are receptors for the immune signal salicylic acid in plants."",""doi"":""10.1038/nature11162"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22699612/"",""year"":""2012"",""journal"":""Nature"",""authors"":""Fu ZQ, Yan S, Saleh A, Wang W, Ruble J, Oka N, Mohan R, Spoel SH, Tada Y, Zheng N, Dong X."",""matched_aliases"":[""NPR1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""32788727"",""title"":""Structural basis of salicylic acid perception by Arabidopsis NPR proteins."",""doi"":""10.1038/s41586-020-2596-y"",""url"":""https://pubmed.ncbi.nlm.nih.gov/32788727/"",""year"":""2020"",""journal"":""Nature"",""authors"":""Wang W, Withers J, Li H, Zwack PJ, Rusnac DV, Shi H, Liu L, Yan S, Hinds TR, Guttman M, Dong X, Zheng N."",""matched_aliases"":[""NPR1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""35545668"",""title"":""Structural basis of NPR1 in activating plant immunity."",""doi"":""10.1038/s41586-022-04699-w"",""url"":""https://pubmed.ncbi.nlm.nih.gov/35545668/"",""year"":""2022"",""journal"":""Nature"",""authors"":""Kumar S; Zavaliev R; Wu Q; Zhou Y; Cheng J; Dillard L; Powers J; Withers J; Zhao J; Guan Z; Borgnia MJ; Bartesaghi A; Dong X; Zhou P"",""matched_aliases"":[""NPR1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""9002272"",""title"":""Characterization of a salicylic acid-insensitive mutant (sai1) of Arabidopsis thaliana, identified in a selective screen utilizing the SA-inducible expression of the tms2 gene."",""doi"":""10.1094/mpmi.1997.10.1.69"",""url"":""https://pubmed.ncbi.nlm.nih.gov/9002272/"",""year"":""1997"",""journal"":""Molecular plant-microbe interactions : MPMI"",""authors"":""Shah J; Tsui F; Klessig DF"",""matched_aliases"":[""NPR1"",""SAI1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""9019406"",""title"":""The Arabidopsis NPR1 gene that controls systemic acquired resistance encodes a novel protein containing ankyrin repeats."",""doi"":""10.1016/s0092-8674(00)81858-9"",""url"":""https://pubmed.ncbi.nlm.nih.gov/9019406/"",""year"":""1997"",""journal"":""Cell"",""authors"":""Cao H; Glazebrook J; Clarke JD; Volko S; Dong X"",""matched_aliases"":[""NPR1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false}]"
LXL04_002409	gene-LXL04_002409	KAL4589502.1	OH-1004	4	Q9SZI3	NPR2_ARATH	Swiss-Prot		Regulatory protein NPR2 OS=Arabidopsis thaliana OX=3702 GN=NPR2 PE=1 SV=1	Arabidopsis thaliana	NPR2	47.203	572	60.557	1.92e-161	489.0	moderate_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At4g26120	水杨酸（SA）结合的底物特异性适配器，属于E3泛素蛋白连接酶复合物（CUL3-RBX1-BTB），介导目标蛋白的泛素化及随后通过蛋白酶体降解（通过相似性预测）。	Salicylic acid (SA)-binding substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).	[]
LXL04_002409	gene-LXL04_002409	KAL4589502.1	OH-1004	1	Q9FDY4	NPR1_ORYSJ	Swiss-Prot		BTB/POZ domain and ankyrin repeat-containing protein NPR1 OS=Oryza sativa subsp. japonica OX=39947 GN=NPR1 PE=1 SV=1	Oryza sativa subsp. japonica	NPR1	52.583	542	56.484	0.0	539.0	moderate_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	Os01g0194300	水杨酸（SA）结合的底物特异性适配器，属于E3泛素蛋白连接酶复合物（CUL3-RBX1-BTB），介导目标蛋白的泛素化及随后通过蛋白酶体降解（通过相似性预测）。	Salicylic acid (SA)-binding substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).	"[{""pmid"":""17309686"",""title"":""Functional analysis of rice NPR1-like genes reveals that OsNPR1/NH1 is the rice orthologue conferring disease resistance with enhanced herbivore susceptibility."",""doi"":""10.1111/j.1467-7652.2007.00243.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/17309686/"",""year"":""2007"",""journal"":""Plant biotechnology journal"",""authors"":""Yuan Y; Zhong S; Li Q; Zhu Z; Lou Y; Wang L; Wang J; Wang M; Li Q; Yang D; He Z"",""matched_aliases"":[""NPR1"",""OsNPR1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""20924648"",""title"":""Role of OsNPR1 in rice defense program as revealed by genome-wide expression analysis."",""doi"":""10.1007/s11103-010-9695-3"",""url"":""https://pubmed.ncbi.nlm.nih.gov/20924648/"",""year"":""2010"",""journal"":""Plant molecular biology"",""authors"":""Sugano S; Jiang CJ; Miyazawa S; Masumoto C; Yazawa K; Hayashi N; Shimono M; Nakayama A; Miyao M; Takatsuji H"",""matched_aliases"":[""NPR1"",""OsNPR1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false},{""pmid"":""22353606"",""title"":""A rice transient assay system identifies a novel domain in NRR required for interaction with NH1/OsNPR1 and inhibition of NH1-mediated transcriptional activation."",""doi"":""10.1186/1746-4811-8-6"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22353606/"",""year"":""2012"",""journal"":""Plant methods"",""authors"":""Chern M, Bai W, Sze-To WH, Canlas PE, Bartley LE, Ronald PC."",""matched_aliases"":[""NPR1"",""OsNPR1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""22694163"",""title"":""OsNPR1 negatively regulates herbivore-induced JA and ethylene signaling and plant resistance to a chewing herbivore in rice."",""doi"":""10.1111/j.1399-3054.2012.01666.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/22694163/"",""year"":""2013"",""journal"":""Physiologia plantarum"",""authors"":""Li R; Afsheen S; Xin Z; Han X; Lou Y"",""matched_aliases"":[""NPR1"",""OsNPR1""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed""],""fulltext_reviewed"":false}]"
LXL04_002409	gene-LXL04_002409	KAL4589502.1	OH-1004	2	Q5D0W8	NPR1_ORYSI	Swiss-Prot		BTB/POZ domain and ankyrin repeat-containing protein NPR1 OS=Oryza sativa subsp. indica OX=39946 GN=NPR1 PE=1 SV=1	Oryza sativa subsp. indica	NPR1	55.02	498	51.768	8.54e-179	533.0	moderate_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10		水杨酸（SA）结合的底物特异性适配器，属于E3泛素蛋白连接酶复合物（CUL3-RBX1-BTB），介导目标蛋白的泛素化及随后通过蛋白酶体降解（通过相似性预测）。	Salicylic acid (SA)-binding substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).	[]