query	query_gene_id	query_protein_id	source_reference	hit_rank	swissprot_acc	swissprot_entry	database_section	target_gene_id	description	organism	homolog_gene_name	percent_identity	alignment_length	query_coverage	evalue	bitscore	confidence	evidence_type	source_db	reference_gene_id	reference_function_zh	reference_function_en	reference_papers_json
LXL04_000788	gene-LXL04_000788	KAL4587911.1	OH-1004	1	Q9SRS9	CHIP_ARATH	Swiss-Prot		E3 ubiquitin-protein ligase CHIP OS=Arabidopsis thaliana OX=3702 GN=CHIP PE=1 SV=1	Arabidopsis thaliana	CHIP	63.669	278	99.627	9.52e-128	366.0	strong_database_homology	BLASTP to reviewed UniProt Swiss-Prot	UniProt Swiss-Prot current_release 2026-06-10	At3g07370	具有 E3 泛素蛋白连接酶活性，可能针对错误折叠的底物进行蛋白酶体降解。	Has E3 ubiquitin-protein ligase activity and may target misfolded substrates towards proteasomal degradation.	"[{""pmid"":""12805616"",""title"":""AtCHIP, a U-box-containing E3 ubiquitin ligase, plays a critical role in temperature stress tolerance in Arabidopsis."",""doi"":""10.1104/pp.103.020800"",""url"":""https://pubmed.ncbi.nlm.nih.gov/12805616/"",""year"":""2003"",""journal"":""Plant physiology"",""authors"":""Yan J, Wang J, Li Q, Hwang JR, Patterson C, Zhang H."",""matched_aliases"":[""AtCHIP"",""CHIP""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""16640601"",""title"":""AtCHIP functions as an E3 ubiquitin ligase of protein phosphatase 2A subunits and alters plant response to abscisic acid treatment."",""doi"":""10.1111/j.1365-313x.2006.02730.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/16640601/"",""year"":""2006"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""Luo J, Shen G, Yan J, He C, Zhang H."",""matched_aliases"":[""AtCHIP"",""CHIP""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""17241447"",""title"":""The chloroplast protease subunit ClpP4 is a substrate of the E3 ligase AtCHIP and plays an important role in chloroplast function."",""doi"":""10.1111/j.1365-313x.2006.02963.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/17241447/"",""year"":""2007"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""Shen G, Yan J, Pasapula V, Luo J, He C, Clarke AK, Zhang H."",""matched_aliases"":[""AtCHIP"",""CHIP""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""17714429"",""title"":""The E3 ligase AtCHIP ubiquitylates FtsH1, a component of the chloroplast FtsH protease, and affects protein degradation in chloroplasts."",""doi"":""10.1111/j.1365-313x.2007.03239.x"",""url"":""https://pubmed.ncbi.nlm.nih.gov/17714429/"",""year"":""2007"",""journal"":""The Plant journal : for cell and molecular biology"",""authors"":""Shen G, Adam Z, Zhang H."",""matched_aliases"":[""AtCHIP""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false},{""pmid"":""20028838"",""title"":""Heat shock protein cognate 70-4 and an E3 ubiquitin ligase, CHIP, mediate plastid-destined precursor degradation through the ubiquitin-26S proteasome system in Arabidopsis."",""doi"":""10.1105/tpc.109.071548"",""url"":""https://pubmed.ncbi.nlm.nih.gov/20028838/"",""year"":""2009"",""journal"":""The Plant cell"",""authors"":""Lee S, Lee DW, Lee Y, Mayer U, Stierhof YD, Lee S, Jürgens G, Hwang I."",""matched_aliases"":[""CHIP""],""evidence"":""UniProt FUNCTION; UniProt/PubMed metadata and gene/species abstract checks; EuropePMC cross-check where available"",""metadata_sources"":[""UniProt"",""PubMed"",""EuropePMC""],""fulltext_reviewed"":false}]"