Species	Reference gene ID	Possible function	Papers / DOI
Arabidopsis	At5g56580	The ANPs-MKK6-MPK4 module is involved in the regulation of plant cytokinesis during meiosis and mitosis.	NQK1/NtMEK1 is a MAPKK that acts in the NPK1 MAPKKK-mediated MAPK cascade and is required for plant cytokinesis.; 2003; DOI: 10.1101/gad.1071103; PMID: 12704083; https://pubmed.ncbi.nlm.nih.gov/12704083/ | The Arabidopsis thaliana MEK AtMKK6 activates the MAP kinase AtMPK13.; 2004; DOI: 10.1016/j.febslet.2004.08.051; PMID: 15474000; https://pubmed.ncbi.nlm.nih.gov/15474000/ | HINKEL kinesin, ANP MAPKKKs and MKK6/ANQ MAPKK, which phosphorylates and activates MPK4 MAPK, constitute a pathway that is required for cytokinesis in Arabidopsis thaliana.; 2010; DOI: 10.1093/pcp/pcq135; PMID: 20802223; https://pubmed.ncbi.nlm.nih.gov/20802223/ | The MAP kinase MPK4 is required for cytokinesis in Arabidopsis thaliana.; 2010; DOI: 10.1105/tpc.110.077164; PMID: 21098735; https://pubmed.ncbi.nlm.nih.gov/21098735/ | AtMPK4 is required for male-specific meiotic cytokinesis in Arabidopsis.; 2011; DOI: 10.1111/j.1365-313x.2011.04642.x; PMID: 21575092; https://pubmed.ncbi.nlm.nih.gov/21575092/ | AtMKK6 and AtMPK13 are required for lateral root formation in Arabidopsis.; 2011; DOI: 10.4161/psb.6.10.17089; PMID: 21904115; https://pubmed.ncbi.nlm.nih.gov/21904115/
Arabidopsis	At4g29810	MEKK1, MKK1/MKK2 and MPK4 function in a signaling pathway that modulates the expression of genes responding to biotic and abiotic stresses and also plays an important role in pathogen defense by negatively regulating innate immunity.	The MKK2 pathway mediates cold and salt stress signaling in Arabidopsis.; 2004; DOI: 10.1016/j.molcel.2004.06.023; PMID: 15225555; https://pubmed.ncbi.nlm.nih.gov/15225555/ | The MAP kinase kinase MKK2 affects disease resistance in Arabidopsis.; 2007; DOI: 10.1094/mpmi-20-5-0589; PMID: 17506336; https://pubmed.ncbi.nlm.nih.gov/17506336/ | Arabidopsis mitogen-activated protein kinase kinases MKK1 and MKK2 have overlapping functions in defense signaling mediated by MEKK1, MPK4, and MKS1.; 2008; DOI: 10.1104/pp.108.120006; PMID: 18599650; https://pubmed.ncbi.nlm.nih.gov/18599650/
Rice	Os01g0510100	Mitogen-activated protein kinase kinase 1.	No verified direct reference in this release