Species	Reference gene ID	Possible function	Papers / DOI
Arabidopsis	At4g04920	Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.	The sfr6 mutant of Arabidopsis is defective in transcriptional activation via CBF/DREB1 and DREB2 and shows sensitivity to osmotic stress.; 2003; DOI: 10.1046/j.1365-313x.2003.01734.x; PMID: 12753580; https://pubmed.ncbi.nlm.nih.gov/12753580/ | Sensitive to freezing6 integrates cellular and environmental inputs to the plant circadian clock.; 2008; DOI: 10.1104/pp.108.123901; PMID: 18614706; https://pubmed.ncbi.nlm.nih.gov/18614706/ | Identification of SFR6, a key component in cold acclimation acting post-translationally on CBF function.; 2009; DOI: 10.1111/j.1365-313x.2008.03763.x; PMID: 19067974; https://pubmed.ncbi.nlm.nih.gov/19067974/ | The Mediator subunit SFR6/MED16 controls defence gene expression mediated by salicylic acid and jasmonate responsive pathways.; 2012; DOI: 10.1111/j.1469-8137.2012.04138.x; PMID: 22494141; https://pubmed.ncbi.nlm.nih.gov/22494141/