﻿Species	Reference gene ID	Possible function	Papers / DOI
Arabidopsis	At2g36490	Bifunctional DNA glycosylase/lyase, which excises 5-methylcytosine (5-meC) and 5-hydroxymethylcytosine (5-hmeC), leaving an apyrimidinic (AP) site that is subsequently incised by the lyase activity.	ROS1, a repressor of transcriptional gene silencing in Arabidopsis, encodes a DNA glycosylase/lyase.; 2002; DOI: 10.1016/s0092-8674(02)01133-9; PMID: 12526807; https://pubmed.ncbi.nlm.nih.gov/12526807/ | DEMETER and REPRESSOR OF SILENCING 1 encode 5-methylcytosine DNA glycosylases.; 2006; DOI: 10.1073/pnas.0601109103; PMID: 16624880; https://pubmed.ncbi.nlm.nih.gov/16624880/ | ROS1 5-methylcytosine DNA glycosylase is a slow-turnover catalyst that initiates DNA demethylation in a distributive fashion.; 2009; DOI: 10.1093/nar/gkp390; PMID: 19443451; https://pubmed.ncbi.nlm.nih.gov/19443451/ | Methylation-independent DNA binding modulates specificity of Repressor of Silencing 1 (ROS1) and facilitates demethylation in long substrates.; 2010; DOI: 10.1074/jbc.m110.124578; PMID: 20489198; https://pubmed.ncbi.nlm.nih.gov/20489198/ | DDM1 and ROS1 have a role in UV-B induced- and oxidative DNA damage in A. thaliana.; 2013; DOI: 10.3389/fpls.2013.00420; PMID: 24155752; https://pubmed.ncbi.nlm.nih.gov/24155752/ | AP endonucleases process 5-methylcytosine excision intermediates during active DNA demethylation in Arabidopsis.; 2014; DOI: 10.1093/nar/gku834; PMID: 25228464; https://pubmed.ncbi.nlm.nih.gov/25228464/ | The carboxy-terminal domain of ROS1 is essential for 5-methylcytosine DNA glycosylase activity.; 2014; DOI: 10.1016/j.jmb.2014.09.010; PMID: 25240767; https://pubmed.ncbi.nlm.nih.gov/25240767/
Arabidopsis	UniProt: Q8LK56	Transcriptional activator involved in gene imprinting.	No verified direct reference in this release
Arabidopsis	At3g10010	Potential transcriptional activator that may act by nicking the target promoter.	No verified direct reference in this release
Rice	Os01g0218032	Bifunctional DNA glycosylase/lyase, which excises 5-methylcytosine (5-meC) and 5-hydroxymethylcytosine (5-hmeC), leaving an apyrimidinic (AP) site that is subsequently incised by the lyase activity (Probable).	A null mutation of ROS1a for DNA demethylation in rice is not transmittable to progeny.; 2012; DOI: 10.1111/j.1365-313x.2012.05009.x; PMID: 22448681; https://pubmed.ncbi.nlm.nih.gov/22448681/ | Mutations in the DNA demethylase OsROS1 result in a thickened aleurone and improved nutritional value in rice grains.; 2018; DOI: 10.1073/pnas.1806304115; PMID: 30275307; https://pubmed.ncbi.nlm.nih.gov/30275307/
Rice	Os05g0445900	Bifunctional DNA glycosylase/lyase, which excises 5-methylcytosine (5-meC) and 5-hydroxymethylcytosine (5-hmeC), leaving an apyrimidinic (AP) site that is subsequently incised by the lyase activity.	A 5-methylcytosine DNA glycosylase/lyase demethylates the retrotransposon Tos17 and promotes its transposition in rice.; 2011; DOI: 10.1073/pnas.1112704108; PMID: 21896764; https://pubmed.ncbi.nlm.nih.gov/21896764/
