Species	Reference gene ID	Possible function	Papers / DOI
Arabidopsis	At4g29810	MEKK1, MKK1/MKK2 and MPK4 function in a signaling pathway that modulates the expression of genes responding to biotic and abiotic stresses and also plays an important role in pathogen defense by negatively regulating innate immunity.	The MKK2 pathway mediates cold and salt stress signaling in Arabidopsis.; 2004; DOI: 10.1016/j.molcel.2004.06.023; PMID: 15225555; https://pubmed.ncbi.nlm.nih.gov/15225555/ | The MAP kinase kinase MKK2 affects disease resistance in Arabidopsis.; 2007; DOI: 10.1094/mpmi-20-5-0589; PMID: 17506336; https://pubmed.ncbi.nlm.nih.gov/17506336/ | Arabidopsis mitogen-activated protein kinase kinases MKK1 and MKK2 have overlapping functions in defense signaling mediated by MEKK1, MPK4, and MKS1.; 2008; DOI: 10.1104/pp.108.120006; PMID: 18599650; https://pubmed.ncbi.nlm.nih.gov/18599650/
Arabidopsis	At4g26070	MEKK1, MKK1/MKK2 and MPK4/MPK6 function in a signaling pathway that modulates the expression of genes responding to biotic and abiotic stresses and also plays an important role in pathogen defense by negatively regulating innate immunity.	ATMPK4, an Arabidopsis homolog of mitogen-activated protein kinase, is activated in vitro by AtMEK1 through threonine phosphorylation.; 2000; DOI: 10.1104/pp.122.4.1301; PMID: 10759527; https://pubmed.ncbi.nlm.nih.gov/10759527/ | The Arabidopsis MAP kinase kinase MKK1 participates in defence responses to the bacterial elicitor flagellin.; 2006; DOI: 10.1111/j.1365-313x.2006.02888.x; PMID: 17059410; https://pubmed.ncbi.nlm.nih.gov/17059410/ | AtMEK1 mediates stress-induced gene expression of CAT1 catalase by triggering H2O2 production in Arabidopsis.; 2007; DOI: 10.1093/jxb/erm144; PMID: 17728292; https://pubmed.ncbi.nlm.nih.gov/17728292/ | AtMKK1 mediates ABA-induced CAT1 expression and H2O2 production via AtMPK6-coupled signaling in Arabidopsis.; 2008; DOI: 10.1111/j.1365-313x.2008.03433.x; PMID: 18248592; https://pubmed.ncbi.nlm.nih.gov/18248592/ | Arabidopsis mitogen-activated protein kinase kinases MKK1 and MKK2 have overlapping functions in defense signaling mediated by MEKK1, MPK4, and MKS1.; 2008; DOI: 10.1104/pp.108.120006; PMID: 18599650; https://pubmed.ncbi.nlm.nih.gov/18599650/ | AtMKK1 and AtMPK6 are involved in abscisic acid and sugar signaling in Arabidopsis seed germination.; 2009; DOI: 10.1007/s11103-009-9503-0; PMID: 19484493; https://pubmed.ncbi.nlm.nih.gov/19484493/
Rice	Os01g0510100	Mitogen-activated protein kinase kinase 1.	No verified direct reference in this release