Species	Reference gene ID	Possible function	Papers / DOI
Arabidopsis	At5g46210	Component of the CUL4-RBX1-CDD (COP10-DDB1a-DET1) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.	CUL4 associates with DDB1 and DET1 and its downregulation affects diverse aspects of development in Arabidopsis thaliana.; 2006; DOI: 10.1111/j.1365-313x.2006.02810.x; PMID: 16792691; https://pubmed.ncbi.nlm.nih.gov/16792691/ | Arabidopsis CULLIN4 Forms an E3 Ubiquitin Ligase with RBX1 and the CDD Complex in Mediating Light Control of Development.; 2006; DOI: 10.1105/tpc.106.043224; PMID: 16844902; https://pubmed.ncbi.nlm.nih.gov/16844902/ | Characterization of Arabidopsis and rice DWD proteins and their roles as substrate receptors for CUL4-RING E3 ubiquitin ligases.; 2008; DOI: 10.1105/tpc.107.055418; PMID: 18223036; https://pubmed.ncbi.nlm.nih.gov/18223036/ | Arabidopsis DDB1-CUL4 ASSOCIATED FACTOR1 forms a nuclear E3 ubiquitin ligase with DDB1 and CUL4 that is involved in multiple plant developmental processes.; 2008; DOI: 10.1105/tpc.108.058891; PMID: 18552200; https://pubmed.ncbi.nlm.nih.gov/18552200/ | Arabidopsis CULLIN4-damaged DNA binding protein 1 interacts with CONSTITUTIVELY PHOTOMORPHOGENIC1-SUPPRESSOR OF PHYA complexes to regulate photomorphogenesis and flowering time.; 2010; DOI: 10.1105/tpc.109.065490; PMID: 20061554; https://pubmed.ncbi.nlm.nih.gov/20061554/ | DWA1 and DWA2, two Arabidopsis DWD protein components of CUL4-based E3 ligases, act together as negative regulators in ABA signal transduction.; 2010; DOI: 10.1105/tpc.109.073783; PMID: 20525848; https://pubmed.ncbi.nlm.nih.gov/20525848/