Species	Reference gene ID	Possible function	Papers / DOI
Arabidopsis	At3g13170	DNA endonuclease, which specifically mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination.	AtSPO11-1 is necessary for efficient meiotic recombination in plants.; 2001; DOI: 10.1093/emboj/20.3.589; PMID: 11157765; https://pubmed.ncbi.nlm.nih.gov/11157765/ | Arabidopsis SPO11-2 functions with SPO11-1 in meiotic recombination.; 2006; DOI: 10.1111/j.1365-313x.2006.02867.x; PMID: 17018031; https://pubmed.ncbi.nlm.nih.gov/17018031/ | The catalytically active tyrosine residues of both SPO11-1 and SPO11-2 are required for meiotic double-strand break induction in Arabidopsis.; 2007; DOI: 10.1105/tpc.107.054817; PMID: 17965269; https://pubmed.ncbi.nlm.nih.gov/17965269/ | A high throughput genetic screen identifies new early meiotic recombination functions in Arabidopsis thaliana.; 2009; DOI: 10.1371/journal.pgen.1000654; PMID: 19763177; https://pubmed.ncbi.nlm.nih.gov/19763177/ | A DNA topoisomerase VI-like complex initiates meiotic recombination.; 2016; DOI: 10.1126/science.aad5196; PMID: 26917763; https://pubmed.ncbi.nlm.nih.gov/26917763/
Rice	Os03g0752200	DNA endonuclease, which specifically mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination.	OsSPO11-1 is essential for both homologous chromosome pairing and crossover formation in rice.; 2010; DOI: 10.1007/s00412-010-0284-7; PMID: 20625906; https://pubmed.ncbi.nlm.nih.gov/20625906/
Rice	UniProt: Q5ZPV8	DNA endonuclease, which specifically mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination.	No verified direct reference in this release